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Glaucoma clinical trials

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NCT ID: NCT04215575 Completed - Clinical trials for Glaucoma, Open-Angle

Baerveldt (BGI) Valve Versus Ahmed(AGV) Valve in Management of Difficult Glaucoma Cases

Start date: January 1, 2014
Phase: N/A
Study type: Interventional

Refractory glaucoma is a difficult subject as many glaucoma devices attempt to reduce IOP. Baerveldt implant is considered as a large implant, and, on the contrary, Ahmed implant is considered a small implant as many comparisons have showed. Investigators have previously used two models S2 and FP7 Ahmed implant. Currently, investigators use Baerveldt implant in refractory glaucoma cases in order to compare it with the Ahmed implant.

NCT ID: NCT04214847 Completed - Clinical trials for Glaucoma, Open-Angle

The Outcome of Ahmed Glaucoma Valve in Difficult Glaucoma Cases

Start date: February 1, 2012
Phase: N/A
Study type: Interventional

The clinical difference (mean IOP, success rate, and complications) on using S2 and FP7 models of Ahmed Glaucoma Valve that had similar dimensions and different materials used for their construction in one year follow up was evaluated.

NCT ID: NCT04202562 Completed - Hypertension Clinical Trials

Efficacy and Safety of ab Interno Trabeculectomy With the Kahook Dual Blade

KDB
Start date: February 2, 2017
Phase: N/A
Study type: Interventional

The Kahook Dual Blade is a single-use device specially designed to create a clean cut in the trabecular meshwork. This ablation in the trabecular meshwork allows a better outflow of the aqueous humor, thus reducing the intraocular pressure (IOP), theoretically beyond the IOP reduction achieved by other minimally invasive glaucoma surgery (MIGS) devices. Studies already published showed good results in terms of the reduction of the number of glaucoma medications and the reduction in the IOP, but not a single study has been performed prospectively comparing the efficacy of the technique, not even with the cataract surgery.

NCT ID: NCT04188015 Completed - Open Angle Glaucoma Clinical Trials

Study of ANX007 in Participants With Primary Open-angle Glaucoma

Start date: July 25, 2018
Phase: Phase 1
Study type: Interventional

This is a double-masked, randomized, sham-controlled study evaluating two dose levels of ANX007 vs sham, administered as repeat Intravitreal (IVT) injections in patients with Primary Open-angle Glaucoma.

NCT ID: NCT04187157 Completed - Cataract Clinical Trials

Association Between Light Spectrum and Survival After Cataract Surgery

Start date: January 1, 2012
Phase:
Study type: Observational

This study was a retrospective observational cohort analysis of subjects aged 65 years and older, who underwent bilateral cataract surgery within a single (15 hospital) healthcare system, to determine the association between type (conventional or blue-light filtering) of implanted intraocular lens and survival.

NCT ID: NCT04172857 Completed - Glaucoma Secondary Clinical Trials

Treatment of Malignant Glaucoma by Anterior Vitrectomy From Two Different Approaches

Start date: May 1, 2015
Phase:
Study type: Observational

To compare the surgical outcomes of treating phacoemulsification with intraocular lens implantation combined with goniosynechialysis (Phaco-IOL-GSL) associated malignant glaucoma (MG), using different incision sites in anterior vitrectomy combined with hyaloidotomy, zonulectomy, and iridectomy (VHZI).

NCT ID: NCT04157530 Completed - Glaucoma Clinical Trials

Clinical Evaluation of Acupuncture in Treating Glaucoma

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

The present study predicts that acupuncture or electroacupuncture can reduce intraocular pressure and also can improve quality of life in patients with glaucoma.

NCT ID: NCT04149899 Completed - Ocular Hypertension Clinical Trials

Safety and IOP-Lowering Effects of WB007

Start date: November 14, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

The study evaluated the safety and IOP-lowering effects of WB007 in adults with primary open-angle glaucoma or ocular hypertension in both eyes. This was a 2-part study. Part 1 was a 3-period dose escalation that evaluated 3 concentrations of WB007 ophthalmic solution following a single dose in one eye. Part 2 was a randomized, double-masked, parallel comparison that evaluated two concentrations of WB007 (selected based on Part 1 results) in both eyes compared with timolol 0.5% for 14 days.

NCT ID: NCT04145830 Completed - Clinical trials for Glaucoma Treatment Using Focused Ultrasound

UCP Glaucoma Treatment for Primary Glaucoma in China

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

To collect safety and efficacy data on Ultrasound Cycle Plasty treatment (UCP) in primary glaucoma asian patients.