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Gingivitis clinical trials

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NCT ID: NCT05524948 Completed - Halitosis Clinical Trials

A Clinical Study to Examine the Effects of an Experimental Toothpaste Compared to a Regular Fluoride Toothpaste on Breath Odor in a Population With Gingivitis

Start date: September 26, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the efficacy of an experimental dentifrice, containing 0.454 percent (%) stannous fluoride and 0.3% zinc chloride, to reduce oral malodor, compared to a marketed regular fluoride dentifrice after 3 weeks twice daily brushing in a population of clinically diagnosed gingivitis.

NCT ID: NCT05441371 Completed - Plaque, Dental Clinical Trials

Antibacterial Effect of Paradontax Toothpaste

Start date: April 21, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to test the antibacterial effect of Parodontax toothpaste on plaque formation, and thus gingivitis compared to placebo toothpaste. Each subject will be given 2 plastic splints that are individually adapted to their quadrant 1 and 2. In the splint in the 1st quadrant, Parodontax test toothpaste will be placed, while in the splint in the 2nd quadrant, regular toothpaste will be placed, which the subject uses daily. Each person's set of teeth is otherwise professionally cleaned.

NCT ID: NCT05389124 Completed - Gingivitis Clinical Trials

Metagenome Resilience in Experimental Gingivitis

Start date: May 23, 2022
Phase:
Study type: Observational

This study aims to identify new biomarkers that indicate the resilience of individuals to developing oral disease. An 'experimental gingivitis' model will be employed in which subjects will refrain from oral hygiene in one quadrant of their mouths for 3 weeks, and will then restore oral hygiene. Gum inflammation will be monitored by clinical measures throughout the trial and samples will be collected for analysis of microbial DNA and RNA.

NCT ID: NCT05363956 Completed - Gingivitis Clinical Trials

Antiplaque Efficacy of Two Novel Commercially Available Herbal Toothpastes.

Start date: September 1, 2021
Phase: Phase 1
Study type: Interventional

Maintaining proper oral hygiene is essential in the prevention of oral as well as general illness. The use of herbal medicine in dentistry is growing exponentially over the years. Today, herbal medicine is considered an effective alternative to manufactured medication. The objective of this current randomized control study is to assess the anti-plaque efficiency of Miswak (Salvadora Persica) and Eucalyptus toothpaste in the treatment of gingivitis. Materials and Methods: This randomized experimental study enrolled 30 healthy individuals as controls and 30 individuals with mild to moderate gingivitis. The study lasted 20 days and included a two-week washout period between Miswak and Eucalyptus toothpaste. The gingival and plaque index were measured at specific time intervals during the research period.

NCT ID: NCT05361590 Completed - Periodontitis Clinical Trials

Impact of Regular Home Use of Lumoral Dual-light Photodynamic Therapy on Plaque Control and Gingival Health

Start date: October 11, 2022
Phase: N/A
Study type: Interventional

This early-stage study is designed to determine the efficacy of the CE-approved, antibacterial, dual-light Lumoral method in periodontitis patients. Improved supragingival plaque control can help to also sustain the subgingival plaque management in the long term. In addition, the device might have a photobiomodulation effect on periodontal tissues.

NCT ID: NCT05326373 Completed - Gingivitis Clinical Trials

Stannous Fluoride and Gingivitis

Start date: April 11, 2022
Phase: N/A
Study type: Interventional

8-week study using stannous fluoride toothpaste on subjects with gingivitis ("unhealthy") and without gingivitis ("healthy"). Gingivitis index will be performed at BL, Week 4 and Week 8. A number of biological samples will be collected at each timepoint.

NCT ID: NCT05268757 Completed - Gingivitis Clinical Trials

Effect of Probiotics on Oral Homeostasis During Oral Hygiene Discontinuation

Start date: January 5, 2022
Phase: N/A
Study type: Interventional

The present study is a double-blinded randomized clinical trial with a duration of 28 days.

NCT ID: NCT05258721 Completed - Periodontitis Clinical Trials

Efficacy of ClōSYS® Sensitive Fluoride Toothpaste and ClōSYS® Sensitive Rinse Regimen on MGI, PI and BOP

Start date: July 6, 2021
Phase: Phase 2
Study type: Interventional

90-day, self-controlled, longitudinal, non-blinded clinical trial which will measure changes in clinical parameters in participants with gingivitis and Stage I or II periodontitis who apply ClōSYS® Sensitive Fluoride Toothpaste and ClōSYS® Sensitive Rinse.

NCT ID: NCT05236322 Completed - Clinical trials for Plasma Cell Gingivitis

Management of Plasma Cell Gingivitis by Two Surgical Techniques

PCG
Start date: January 1, 2022
Phase:
Study type: Observational

Two surgical protocols for management of Plasma cell Ginigivitis; either by surgical enblock resection of cold laser resection

NCT ID: NCT05146557 Completed - Obesity Clinical Trials

Associations Between Obesity, Dental Caries, Erosive Tooth Wear and Periodontal Disease in Adolescents: A Case Control-study

Start date: July 1, 2015
Phase:
Study type: Observational

Objectives To compare oral health (dental caries, periodontal status, and erosive tooth wear (ETW)), diet and oral hygiene habits between obese and normal weight adolescents, and to explore possible risk associations. Materials and Methods In this case-control study, a convenient sample of 81 obese adolescents (age range 11-18) from a rehabilitation centre, and 81 age-sex-matched normal weight adolescents were selected. Groups were defined using the Body Mass Index and growth curves for Flemish. Oral health was measured using DMFT, gingival, plaque and BEWE index. A validated questionnaire was utilized to assess diet and oral hygiene habits.