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Gingival Recession clinical trials

View clinical trials related to Gingival Recession.

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NCT ID: NCT05565079 Recruiting - Recession, Gingival Clinical Trials

Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative

Start date: October 6, 2022
Phase: Phase 4
Study type: Interventional

24 patients will be treated with a coronally positioned tunnel with AlloDerm RTM with or without the addition of Enamel Matrix Derivative to compare the baseline and 6-month changes in recession defect coverage, clinical attachment levels, amount of keratinized tissue width, and soft tissue thickness.

NCT ID: NCT05563428 Recruiting - Gingival Recession Clinical Trials

Free Gingival Graft Versus Connective Tissue Graft

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

This study wil compare FGG and CTG for recession coverage in the anterior mandibula.

NCT ID: NCT05395923 Recruiting - Gingival Recession Clinical Trials

The Effects of Palatal Pre-sutures in Connective Tıssue Graft Surgery

Start date: January 9, 2023
Phase: N/A
Study type: Interventional

Connective tissue graft operation is one of the most frequently performed surgical procedures to increase the width of the attached gingiva and to treat gingival recessions. The most preferred donor site during this operation is the palatal mucosa.Reported postoperative complications are usually related to the donor site. Problems such as prolongation of bleeding time, delay in wound healing and severe pain in the palatal region where the graft is taken are frequently encountered. Bleeding control in the palatal donor area is very important for patient comfort. Additional measures may be required to control bleeding, such as sutures with or without hemostatic agents, or acrylic, plastic palatal stents and periodontal pastes prepared before the operation. Suturing the Greater Palatine Artery (GPA) or terminal vessel branches has been shown to be an effective method to control palatal bleeding. Therefore the aim of this study is to evaluate the effectiveness of the pre-suture method applied in the palatal region before the connective tissue graft is taken in reducing hemostasis.Pre-suture method can increase the operator's field of vision and operational comfort. Patient-reported outcomes such as the amount of pain and bleeding in the palatal donor area during and after surgery, painkiller intake, number of days of discomfort, satisfaction, quality of life, and willingness to be treated will be evaluated. In addition, it will be evaluated whether this suture technique affects the healing of the half-thickness flap in the palatal region after obtaining a connective tissue graft with a single incision method.

NCT ID: NCT05370456 Recruiting - Clinical trials for Gingival Recession, Generalized

Adjunctive Use of Hyaluronic Acid in Multiple Coronally Advanced Flap

Start date: May 3, 2022
Phase: N/A
Study type: Interventional

The primary aim of this study is to evaluate whether the effect of HA in combination with XCM for the treatment of MAGRs with a multiple coronally advanced flap technique (mCAF) achieves better results than the XCM with mCAF alone in terms of recession reduction (primary outcome) and other secondary root coverage outcomes (e.g. complete root coverage, mean root coverage). Moreover, this study aims to compare secondary clinical variables (e.g. keratinized tissue width (KTW) changes, probing pocket depth (PPD) changes, volumetric gain (VG), etc.), also with a digital approach, the patient-reported outcome measures (PROMs e.g. pain, swelling, bleeding) and lastly the expression of molecular mediators of tissue healing/regeneration. The hypothesis of this study is that at 6 months and 1 year follow-up the mCAF with XCM+HA is superior to the mCAF with only XCM in terms of recessions reduction and secondary clinical variables, including PROMs.

NCT ID: NCT05287763 Recruiting - Gingival Recession Clinical Trials

Efficacy of Collagen Sponge on Palatal Wound Healing

Start date: April 30, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to compare the efficacy of collagen sponge and gelatin sponge on the palatal wound healing and postoperative pain following gingival graft harvesting.

NCT ID: NCT05270161 Recruiting - Gingival Recession Clinical Trials

The Tunnel Technique and Free Gingival Graft in Gingival Recessions Treatment

Start date: November 5, 2021
Phase: N/A
Study type: Interventional

The present study aims to compare the tunnel technique/laterally closed tunnel technique and the FGG technique in the treatment of isolate/multiple GR in the anterior region of the mandible. Furthermore, it is proposed to evaluate the effect of a gel based on hyaluronic acid and green tea on the healing of the donor area after the removal of FGG from the palate. This work is expected to contribute to the still uncertain literature on the effectiveness of the tunnel technique as an alternative to the use of FGG in the treatment of multiple GR in the mandible.

NCT ID: NCT05045586 Recruiting - Gingival Recession Clinical Trials

MCAT With HA and sCTG Compared With sCTG Alone for Treatment of Multiple Gingival Recession: Clinical Trial

Start date: September 15, 2021
Phase: N/A
Study type: Interventional

Microsurgical tunneling flap procedures using connective tissue grafts (CTG) are predictable for treating teeth with gingival recessions. Cross-linked hyaluronic acid can be used in conjunction with subepithelial palatal connective tissue grafts to improve postsurgical results. The aim of this study is to evaluate clinically the use of tunnel technique with CTG and cross-linked hyaluronic acid in addition to CTG alone for the treatment of multiple gingival recessions.

NCT ID: NCT04980066 Recruiting - Gingival Recession Clinical Trials

Evaluation of Sticky Bone With or Without EDTA for Treatment of Gingival Recession

Start date: August 3, 2021
Phase: N/A
Study type: Interventional

Gingival recession is a common clinical finding in periodontal disease which is frequently associated with esthetic concerns, root hypersensitivity, and root caries. Many surgical therapeutic approaches have been developed to predictably obtain root coverage of gingival recession defects. Injectable PRF (I-PRF) is the liquid form of PRF. I-PRF is a bioactive agent obtained by low-speed centrifugation, and it has the capacity to stimulate tissue regeneration. At high concentrations, PRF may stimulate the secretion of several growth factors and trigger fibroblast migration. I-PRF is generally used in regenerative treatments, with good outcomes. Ethylenediaminetetraaceti acid (EDTA) is a chelating agent that could enhance the attachment of connective tissue to the root surface by exposing collagen and, as a consequence, enhance root coverage. EDTA works at neutral pH, and this property has been reported to preserve adjacent tissue vitality. The present study will be carried out to evaluate the effect of sticky bone with or without EDTA root surface biomodification for treatment of gingival recession.

NCT ID: NCT04920136 Recruiting - Gingival Recession Clinical Trials

Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix

Start date: September 17, 2021
Phase: N/A
Study type: Interventional

This study is to compare the two techniques to achieve change in the tissue quality at areas of lack of Keratinized Tissue (KT) using soft tissue grafting with autogenous graft material (Free Gingival Graft)(FGG) vs Strip gingival graft with acellular dermal matrix (ADM) (SGG+ADM).

NCT ID: NCT04800250 Recruiting - Gingival Recession Clinical Trials

Treatment of Multiple Gingival Recession Defects Using a New Xenogenic Collagen Membrane Compared to Connective Tissue Graft: a Randomized Controlled Split-mouth Clinical Study

Mucogreffe
Start date: July 24, 2023
Phase: N/A
Study type: Interventional

Limitation of donor site and significant postoperative morbidity are often described in connective tissue graft. We want to show if mucogain matrix used in tunnel technique to recover RTI Cairo recessions defects could be an alternative to connective tissue graft