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Ganglion Cysts clinical trials

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NCT ID: NCT02651519 Completed - Sleep Deprivation Clinical Trials

Sleep Quality After Stellate-ganglion Block of Patients Undergoing Breast Cancer Operation

Start date: January 2016
Phase: Phase 4
Study type: Interventional

Stellate-ganglion block have been done safely for more than 60 years. It has proved to provide survivors of breast cancer with relief from hot flushes and sleep dysfunction with few or no side-effects. The aim of the present study is to evaluate postoperative sleep quality of patients undergoing breast cancer surgery with Stellate-ganglion block performed in the operation.

NCT ID: NCT02624661 Terminated - Clinical trials for Trigeminal Neuralgia

Glycerol Block of the Trigeminal Ganglion in Trigeminal Neuralgia Using a New Neuronavigation-based Surgical Technique

Start date: May 2016
Phase: Phase 1/Phase 2
Study type: Interventional

Trigeminal neuralgia is one of the strongest pains known to humans. Some patients do not have enough effect with the available pharmaceutical treatments and are offered a type of surgery, which involves the injection of glycerol in a nerve structure called trigeminal ganglion. The researchers will do a pilot study on 10 patients with a new surgical technique using neuronavigation. The researchers believe that this new neuronavigation-based system can improve the precision of the technique and reduce the risk for complications.

NCT ID: NCT02553876 Terminated - Clinical trials for Dorsal Root Ganglion Stimulation

Dorsal Root Ganglion Stimulation for Hand and Upper Limb Pain

Start date: September 2015
Phase:
Study type: Observational

There are no studies as yet specifically investigating the application of DRG stimulation in the treatment of chronic pain affecting the upper limbs. The investigators propose to investigate the effect of dorsal root stimulation in patients with chronic hand or upper limb pain.

NCT ID: NCT02407886 Completed - Ganglion Cells Clinical Trials

Retinal Ganglion Cell Layer in Patients With Intracerebral Processes

Start date: March 2015
Phase: N/A
Study type: Observational

Transsynaptic degeneration of the retinogeniculate pathways is well documented to occur in nonhuman primates when the cerebral lesion occurs even during adulthood. In case of humans, retrograde transsynaptic degeneration of the retinogeniculate pathways has been shown to occur following prenatal or perinatal lesions, but its occurrence after cerebral lesions in adults is considerable rare. It is, however, well established that retrograde transsynaptic degeneration affects other neural systems in humans even when the injury occurs during adulthood. Some histopathological evidence points to the possibility of transsynaptic degeneration of the retinogeniculate pathway in humans even when the lesion occurs in adults, but the clinical significance is unknown.' Purpose: To measure the retinal ganglion cell layer (GCL) in patients with visual field defects due to intracerebral processes. To correlate GCL with the localization and type of intracerebral lesion. To compare the GCL with the retinal nerve fibre layer (RNFL) to investigate, which of the 2 parameters is more sensitive to show retinal layer abnormalities. To correlate GCL with visual field defects and electrophysiological parameters.

NCT ID: NCT02319694 Completed - Parkinson's Disease Clinical Trials

Intraoperative Analysis of Reward and Impulsivity in the Basal Ganglia

Start date: July 2013
Phase:
Study type: Observational

This project studies the impulsive side effects of common treatments for Parkinson's Disease. By learning how parts of the brain involved in Parkinson's encode information related to reward and motivation, the investigators will better understand the reasons why Parkinson's patients often suffer from compulsive gambling, hypersexuality, and repetitive tinkering ("punding"). These results may lead to the design of better methods of deep brain stimulation (DBS) that minimize the behavioral side effects of Parkinson's treatment.

NCT ID: NCT02295163 Withdrawn - Prostate Cancer Clinical Trials

Stellate Ganglion Block for Hot Flushes in Men Treated With ADT

Start date: July 2014
Phase: N/A
Study type: Interventional

Androgen deprivation therapy (ADT) is widely used as standard therapy in the treatment of locally advanced and metastatic prostate cancer. Hot flushes and night sweats are one of the main side-effects of ADT. There are no successful and well-tolerable treatment options available. A possible treatment for hot flushes is stellate-ganglion block (SGB), used as a means of interrupting parts of the sympathetic nervous system involved in temperature regulation. Objective of this study: To assess the short-term efficacy of stellate ganglion block on hot flush reduction versus sham procedure

NCT ID: NCT02181205 Withdrawn - Clinical trials for Postdural Puncture Headache

Sphenopalatine Ganglion Block for Post-Dural Puncture Headache

Start date: November 2014
Phase: N/A
Study type: Interventional

The investigators are attempting to determine a less invasive method of treatment for postdural puncture headaches that can occur after regional anesthesia. The investigators will be evaluating the relief of headache with those subjects receiving treatment with a sphenopalatine ganglion block with bupivacaine versus placebo, evaluating the incidence of epidural blood patch, pain score of headache at 1 hour, then 24, 48, and 72 hours lower with post study treatment versus placebo, and potential side effects of those patients receiving study therapy as well as epidural blood patch.

NCT ID: NCT02154789 Terminated - Ganglion Cysts Clinical Trials

An Assessment of Intra-lesional 3% Polidocanol Solution in the Treatment of Digital Myxoid Cyst

Start date: July 27, 2015
Phase: Phase 4
Study type: Interventional

Digital myxoid cysts arise from degeneration in the connective tissue of the digit joint, usually the last joint of the finger or toe, often due to underlying joint arthritis. They may connect with the joint. Pressure from the cyst can result in deformity of the digit's nail and trauma to the cyst results in leakage of the fluid, representing a potential source of entry for infection. Cysts can be tender and interfere with the digit's function. A variety of treatments are available, from simple extrusion which is rarely successful, to more destructive cryotherapy, infra-red coagulation and formal excision under local anaesthetic. These latter three approaches can result in considerable scarring. Sclerosant injection of polidocanol in one small non-randomised trial has been reported to be a well tolerated efficacious treatment with minimal scarring and long-term resolution. Following a pilot study, the investigators aim to trial this treatment to assess efficacy in a larger population.

NCT ID: NCT02055911 Withdrawn - Clinical trials for Diabetic Macular Edema

Retinal Ganglion Cell Function After Intravitreous Ranibizumab in Patients With Diabetic Macular Edema

Start date: March 2014
Phase: Phase 4
Study type: Interventional

To evaluate the safety of intravitreal ranibizumab repeated injections in patients with diabetic macular edema regarding maintenance of retinal ganglion cell function.

NCT ID: NCT02029235 Terminated - Trigger Finger Clinical Trials

Post-operative Analgesia in Elective, Soft-tissue Hand Surgery

Start date: February 10, 2015
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to find out which combination of pain medications following surgery work the best and result in the fewest side effects.