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Gait, Hemiplegic clinical trials

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NCT ID: NCT06436898 Not yet recruiting - Stroke Sequelae Clinical Trials

Proof of Concept of Hybrid Robotics for Gait Rehabilitation of Persons Post-stroke

PoCH-Rehab
Start date: September 1, 2024
Phase: N/A
Study type: Interventional

Persons post-stroke suffer from hemiparesis affecting the functional abilities of the controlesional lower limb. Improving walking is therefore a primary rehabilitation goal for such patients. Robotic-Assisted Rehabilitation (RAR, e.g. exoskeletons) and Functional Electrical Stimulation (FES) are promising techniques to facilitate the functional recovery after stroke. allowing benefits to be maintained over long term.

NCT ID: NCT06327035 Not yet recruiting - Stroke Clinical Trials

Evolution of Walking Abilities in Subacute Stroke Patients Hospitalized in Neurorehabilitation Center

PROWALK
Start date: March 26, 2024
Phase:
Study type: Observational

The goal of this observational study is to describe the evolution of gait recovery during the subacute phase of stroke up to six months after stroke, in patients hospitalized in medical and neurological rehabilitation units.

NCT ID: NCT06299943 Recruiting - Stroke Clinical Trials

Biofeedback Gait Training by Target Biomechanical Parameters in the Early Recovery Period of Stroke

TargetGait
Start date: January 24, 2022
Phase: N/A
Study type: Interventional

Single-blinded controlled clinical trial. Biofeedback training courses based on target biomechanical gait parameters are being studied. For targeted biofeedback training, various biomechanical parameters are used: parameters of the gait cycle, EMG or kinematics of joint movements. The number of sessions is 8-11 for each patient. Clinical gain analysis is carried out before and after a course of training. Changes in biomechanical parameters that occurred at the end of the training course are assessed in comparison with those before training, and both statuses (before and after training) are compared with similar gait parameters in a group of healthy adults.

NCT ID: NCT06170814 Recruiting - Cerebral Palsy Clinical Trials

Effects of Different Focuses of Attention on Walking and Balance in Children With Cerebral Palsy

Start date: December 30, 2023
Phase:
Study type: Observational

This study was planned to examine the effects of different focuses (external and internal focus)of attention on functional walking and balance in children with cerebral palsy. Individuals with CP between the ages of 6-18 will be included in the research. It was planned to include 24 individuals in total, 12 individuals in each group.

NCT ID: NCT06113965 Recruiting - Stroke Clinical Trials

Neural Operant Conditioning

Start date: May 31, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn if operant conditioning can reduce spasticity in order to improve walking in stroke patient. The main questions it aims to answer are: - Can participants self-regulate reflex excitability - Can participants self-regulate reflex, reduce spasticity and improve walking Participants will undergo surface stimulation to evoke spinal reflexes and will be asked to control these reflexes therefore reducing spasticity. Researchers will compare result to able bodied participants to see if [insert effects]

NCT ID: NCT06061601 Recruiting - Stroke Sequelae Clinical Trials

ACTive Exoskeleton for Unilaterally-Assisted Locomotion (ACTUAL)

ACTUAL
Start date: April 12, 2021
Phase: N/A
Study type: Interventional

Walking difficulties are common symptoms after stroke, significantly reducing quality of life. Walking recovery is therefore one of the main priorities of rehabilitation. Wearable powered exoskeletons have been developed to provide lower limb assistance and enable training for persons with gait impairments by using typical physiological movement patterns. Exoskeleton were originally designed for individuals without any walking capacities, such as subjects with a complete spinal cord injury. Recent systematic reviews suggested that lower limb exoskeletons could be valid tools to restore independent walking in subjects with residual motor function, such as persons post-stroke.The aim of the study was to identify the end-users needs and to develop a user-centered-based control system for the TWIN lower limb exoskeleton to provide an efficient post-stroke rehabilitation of gait. The investigators thus carried out the development and validation through evaluation sessions performed on healthy clinical experts and persons with stroke to evaluate TWIN-Acta usability, acceptability, and barriers of usage. A phase two includes a pilot study of efficacy of using the TWINActa for gait rehabilitation for persons with stroke.

NCT ID: NCT05945966 Completed - Stroke, Ischemic Clinical Trials

Effects of Bilateral Versus Unilateral Lower Limb Training on Balance and Gait Parameters in Stroke Patients

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

To determine the effects of bilateral versus unilateral lower limb training on balance and gait parameters in stroke patients

NCT ID: NCT05908149 Recruiting - Gait, Hemiplegic Clinical Trials

Gait Analysis in Patients With Hemiplegia Using Insole Splint.

Start date: April 12, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the gait of patients with hemiplegia, with or without the use of insole splint. The main questions it aims to answer are: Does the insole splint improve the gait of these patients? Does any difference exist in the use of muscles? Participants will have to walk in the gait analysis' aisle with and without the insole splint, using wireless EMG device.

NCT ID: NCT05740540 Recruiting - Stroke Clinical Trials

Implant for Walking After Stroke

Start date: May 16, 2023
Phase: N/A
Study type: Interventional

This is a device study that will evaluate the effect of an implanted stimulator on improving walking in stroke survivors. There are two phases in the study: 1) Screening - this phase determines if the individual is a good candidate to receive an implanted system, 2) Implantation, controller development, and evaluation - this phase includes installing the device and setting the individual up for home use, creating advanced controllers for walking and evaluating the effect of the device over several months.

NCT ID: NCT05740228 Recruiting - Stroke Clinical Trials

Transcranial Direct Current Stimulation for Gait Recovery Following Stroke

TransGait
Start date: March 1, 2023
Phase: N/A
Study type: Interventional

Background: Stroke is a leading cause of adult disability. The ability to walk is considered as the most important physical activity in daily life and strongly associated with quality of life in patients with stroke sequela. Conventional transcranial Direct Current Stimulation (tDCS) can induce mixed effects to improve gait impairment after stroke. The problem of limited focal specificity of tDCS may lead to an ineffective stimulation and in turn may be reduced the potential application of tDCS in clinical routine. High-definition transcranial Direct Current Stimulation (HD-tDCS) allows inducing, in a non-invasive way, a transient excitatory neuromodulation of a given cerebral region and to obtain a very focused cortical effect. However, the clinical and neurophysiological effects of HD-tDCS remain largely unknown for enhancing gait recovery in patients with stroke. The investigators hypothesize that anodal HD-tDCS will enhance neural interactions between motor networks and, thereby, improve motor processing and gait relearning. The investigators propose to carry out a study on chronic stroke patients involving anodal HD-tDCS of the affected primary motor cortex combined with a physical therapy. This study has three main objectives: - To compare the effects of two techniques of tDCS (anodal tDCS, anodal HD-tDCS) on clinical recovery in patients with chronic stroke. - To assess the effects of these brain stimulation techniques on brain reorganization with electroencephalography (EEG). - To assess the effects of these brain stimulation techniques on spatiotemporal gait parameters during walking with wearable motion sensors. Methods: 36 patients with ischemic or hemorrhagic stroke will be randomly assigned to one of 3 groups: anodal tDCS, anodal HD-tDCS, or sham stimulation. Each group will receive the corresponding stimulation therapy 3 times per week for 2 weeks, simultaneously with physical therapy. Before (T0) and immediately after the treatment period (T1) and again one month later (T2), standardized assessments of sensorimotor function areas are obtained together with spatio-temporal analysis. Brain reorganization is assessed with EEG before and immediately after the treatment period. These recordings will be used to compare and investigate the clinical and physiological effects of each treatment modality.