Aging Clinical Trial
Official title:
Effects of Resistance Training With High vs. Light-moderate Loads on Muscle-tendon Function in the Elderly
There are no unbiased studies that have analyzed the effects of resistance training with
traditional, heavy versus light-moderate loads on muscle, tendon and bone in elderly people.
The purpose of the present study is to assess the effects on muscle mass and function, tendon
and bone of two different training intensities, light-moderate vs. heavy load, in people
older than 65 years old.
The study will be carried out with a randomized controlled design. Participants will perform
single training sessions and a 12-wk dynamic resistance training program on the knee
extensors with different training intensities on each leg. One leg will train with heavy
loads and the other one will train with light-moderate loads, but matching the load x
repetitions performed by the contralateral side.
The decline in muscle function provoked by the aging process and frailty are directly related
to decreases in mobility and the ability to perform the so called "daily life activities".
Resistance training is especially useful at this stage, given that it is an effective and
widely applicable intervention to control and revert sarcopenia, and the deterioration of
tendon and bone function. Despite of the effectiveness of heavy load resistance training, a
controversy has arisen in the last years about the effects of lower load resistance training
programs to achieve similar adaptations. This is because most of the studies that have
compared light-moderate versus heavy load programs did not control the differences in total
training load, measured as the overall mechanical work performed during the training program.
Therefore, there are no unbiased studies that have analyzed the effects of resistance
training with traditional, heavy versus light-moderate loads on muscle, tendon and bone in
elderly people.
The purpose of the present study is to assess the effects on muscle mass and function, tendon
and bone of two different training intensities, light-moderate vs. heavy load, in people
older than 65 years old.
The studies will be carried out with a crossover (acute training sessions) and randomized
controlled design (longitudinal training intervention). Participants will perform single
training sessions with each resistance training intensity and a 12-wk dynamic resistance
training program on the knee extensors with different training intensities on each leg. One
leg will train with heavy loads and the other one will train with light-moderate loads, but
matching the load x repetitions performed by the contralateral side. Muscle adaptations (EMG,
muscle size and architecture), tendon mechanical properties, bone mineral density, blood
parameters and life quality will be analyzed before and after the cessation of the training
program.
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