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Fractures, Bone clinical trials

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NCT ID: NCT05500677 Completed - Analgesia Clinical Trials

Lidocaine Spray for Pain Control in Rib Fractures

Start date: June 1, 2021
Phase: Phase 4
Study type: Interventional

In this study, we aimed to compare the analgesic efficacy of lidocaine spray with tramadol hydrochloride and fentanyl citrate in rib fractures.

NCT ID: NCT05489952 Recruiting - Hip Fractures Clinical Trials

Iron Supplementation for Geriatric Hip Fractures

Start date: September 15, 2022
Phase: Phase 4
Study type: Interventional

Geriatric hip fracture is an important disease that affects the health life of the elderly in China. Geriatric hip fracture is often complicated by a variety of comorbidities due to advanced age. And anemia is a common comorbidity. At present perioperative management of geriatric hip fracture, transfusion is only indicated for moderate and severe anemia, while no special medical intervention for mild anemia in China. More and more studies have found that iron can not only correct anemia, but also improve cardiac function, patients' quality of life and function. This study investigated the effect of perioperative iron supplementation on activity tolerance in elderly patients with hip fracture complicated with iron deficiency anemia. The study was a randomized, parallel controlled clinical study. Due to the requirements of the ethics committee, the unblinded setting was cancelled due to ethical considerations. Research will be grouped according to whether to accept iron supplementation treatment, are divided into 2 groups, respectively, iron treatment group and the traditional method. The method of randomization was stratified block randomization. The experimental group added to the intravenous iron sucrose during perioperative period according to the degree of iron deficiency. If there is still a iron deficiency or anemia at discharge, oral ferrous lactate is added after discharge. The outcomes include 6-minute walk distance, Harris score, EQ-5D score six months after surgery, perioperative blood transfusion rate, and so on in the two groups.

NCT ID: NCT05489185 Not yet recruiting - Hip Fractures Clinical Trials

Clinical Trial to Assess the Efficacy of Tranexamic Acid in Reducing Blood Loss in Hip Fracture Patients.

Start date: May 30, 2023
Phase: Phase 4
Study type: Interventional

Hip fracture in elderly patients is a pathology with a high economic and health impact on the patient himself and on the National Health System, especially considering the significant aging of the population of the Basque Country. Despite advances, hip fracture remains in the clinical groups with the highest in-hospital mortality. Hip fracture is associated with numerous adverse events and high mortality. Numerous antifibrinolytics, such as tranexamic acid (TXA), have been used to limit bleeding in orthopedic surgery and thus prevent the need for blood transfusion. Numerous studies have shown that the use of tranexamic acid does not increase the risk of thrombosis. It is proposed to carry out clinical research with drugs without commercial interest. A randomized, double-blind clinical trial to assess the efficacy of tranexamic acid in reducing blood loss in elderly patients with hip fracture.

NCT ID: NCT05488080 Not yet recruiting - Pain Clinical Trials

PAINED: Project Addressing INequities in the Emergency Department

PAINED
Start date: August 1, 2024
Phase: N/A
Study type: Interventional

Racial and ethnic inequities in health care quality have been described across a broad range of clinical settings, patient populations, and outcomes. Our overarching goal is to eradicate health care inequities through evidence-based interventions. The objectives of this proposal are to develop and test the impact of two interventions on overcoming clinician implicit bias and mitigating inequities in the management of pain among children seeking care in the emergency department for the treatment of appendicitis or long bone fractures.

NCT ID: NCT05483387 Recruiting - Arthrosis Clinical Trials

Prospective Post-market Clinical Follow-up Study of the HBS 2 Resorb Mg in Patients With Intra- and Extraarticular Fractures, Pseudarthroses and Arthrodesis of Small Bones and Bone Fragments.

Start date: November 1, 2022
Phase: Phase 4
Study type: Interventional

This study is a multi-centre, prospective, clinical observational study to evaluate the CE-marked HBS 2 Resorb Mg screws under routine conditions. The device will be used according to its intended use. The data collected for this study does only include measurements which are standard of care.

NCT ID: NCT05481671 Recruiting - Traumatic Fracture Clinical Trials

Influencing Factors and Their Approach of Kinesiophobia in Patients With Traumatic Fractures

Start date: October 2, 2022
Phase:
Study type: Observational

This study aims to investigate the relationship between kinesiophobia and pain catastrophizing, as well as the relationship between pain catastrophizing and pain level, anxiety and depression, self-efficacy and psychological resilience in patients with traumatic fractures, and to explain the approach and effect relationship between kinesiophobia and these variables.

NCT ID: NCT05470257 Enrolling by invitation - Clinical trials for Fracture of Radius and Ulna

Randomized Control Trial: Elbow Extension Versus Flexion Cast in Proximal Half Both Bone Forearm Fractures

Start date: April 7, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to compare outcomes between two immobilization methods for pediatric proximal half both bone forearm fractures.

NCT ID: NCT05467644 Recruiting - Bone Loss Clinical Trials

Treatment of Fracture Related Infection in Latin America.

Start date: January 1, 2021
Phase:
Study type: Observational

Postoperative bone infection is a severe complication in the treatment of fractures and is more frequent than in elective joint replacement surgeries. Surgical treatment is based on meticulous debridement of bone and soft tissue, dead space management, soft tissue reconstruction when necessary, and restoration of bony stability in the non-union fracture. In addition, local antibiotic therapy is recommended in certain circumstances. This study aims to evaluate the results of surgical treatment of fracture-related infection in Latin America.

NCT ID: NCT05467618 Completed - Fractures, Bone Clinical Trials

Comparison of Surgical Approaches in Reducing Mandibular Angle Fracture

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

This study compared the surgical approach to the lower jaw fractures, an approach from the face and an approach from inside the mouth were used and compared for the outcomes.

NCT ID: NCT05465382 Recruiting - Clinical trials for Intra-Articular Fractures

Intra Articular Ankle Fractures

Start date: July 22, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the effect of early, percutaneous, intra-articular saline lavage on the undiluted synovial fluid microenvironment during the acute phase following intra-articular fracture of the human ankle. We hypothesize that early intervention with percutaneous joint lavage in the first 0-48 hours after injury will attenuate the production of pro-inflammatory cytokines, MMP's and cartilage breakdown products compared to non-lavaged control subjects at the time of surgical fixation.