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Fractures, Bone clinical trials

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NCT ID: NCT03859999 Completed - Colles' Fracture Clinical Trials

PRediction of Outcome With ED Intervention for Colles Type Wrist Fractures [PREDICT]

PREDICT
Start date: November 1, 2017
Phase:
Study type: Observational

The Colles fracture, a fracture of the wrist, is frequently associated with deformity of the broken part of the bone, particularly in older or frail patients. This can cause long term wrist deformity and problems using the wrist and hand if not corrected. Manipulation under anaesthesia (MUA) is often undertaken in the emergency department (ED) for 'displaced' fractures in an attempt to correct the deformity. The procedure involves a local anaesthetic technique, additional staff, and takes some time to complete. The procedure is not without risk; it can cause bruising, skin tears, complications from the local anaesthetic and can be uncomfortable. Although fracture positions are usually improved by ED manipulation initially; these fractures can slip back to an unacceptable position over the next 1-2 weeks, despite plaster cast immobilisation. For fractures that slip, open surgery is usually required to correct and hold the fracture with metal plates or wires. This is performed in the operating theatre and requires another visit to the hospital. Preliminary work suggests this affects over a quarter of patients, undergoing ED MUA for Colles' wrist fractures. If it were possible to reliably identify patients whose fractures were likely to slip and require open surgery despite ED manipulation, unnecessary procedures and visits to hospital could be avoided. This would ensure patients got the right treatment first time and save patients and the NHS time and money. There are a number of factors that might affect the likelihood of fracture instability and need for surgery. These include patient factors such as age, functional status and presence of osteoporosis (thin weak bones) and the specific position of the fracture. In this study we will be measuring the fracture positions on x-rays of patients with a Colles' fracture to see if we can accurately predict ED MUA failure on the initial x-ray.

NCT ID: NCT03856502 Completed - Cognition Disorders Clinical Trials

Influence of Intrathecal Dexamethasone Administration for Proximal Femoral Fractures

Start date: November 11, 2012
Phase: N/A
Study type: Interventional

Spinal anesthesia blocks acute pain in older patients with femur fracture. Delirium is a common complication seen after femur fracture, affecting approximately 10-16% of patients. It is associated with increased mortality at 1st year, delayed rehabilitation efforts, prolonged length of hospital stay, poorer functional outcomes, and increased risk of nursing home placement. Intrathecal dexamethasone administration improves quality of anesthesia in patients with femur fracture compared to conventional spinal anesthesia.

NCT ID: NCT03853330 Completed - Clinical trials for Fracture; Rib, Multiple

Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Patients With Multiple Fracture Ribs

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

To assess the analgesic and respiratory effect of continuous Erector Spinae Plane block versus Thoracic Epidural in patients with multiple fracture ribs.

NCT ID: NCT03852095 Completed - Fractures, Bone Clinical Trials

Single Time Management Diseases in Pediatric Traumatology

Start date: November 2, 2018
Phase:
Study type: Observational [Patient Registry]

A recent internal study evaluating the relevance of the visit to traumatology consultation in our establishment highlight that 49.3% of consultations were not relevant passages. The project consists of individualizing 5 to 6 pathologies and to create care sheets and patient sheets to be given to the care teams and patients when the pathology lends itself to it. The aim is to reduce the irrelevant passage rate during these consultations, which is the source of absence from iterative work for parents, collateral expenses (toll, parking), absence from school for the children, unjustified expenses and X-ray examination unnecessary most often.

NCT ID: NCT03849014 Completed - Hip Fractures Clinical Trials

Comparison of Biochemical Changes in Patients With Trochanteric Region Fracture Fixation With DHS Versus PFN

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Hip fractures are one of the most frequent fractures in older adults. There is still controversy which surgical strategy is the best option for treatment of hip fractures especially trochanteric region fractures. Surgical intervention that follows hip fracture induces biochemical, physiological and fibrinolytic changes that are so-called "second hit phenomenon" which trigger systemic inflammatory response syndrome. The investigators are aiming to study this phenomenon after two different surgical procedures and help surgeons in everyday practice to choose the most suitable surgical treatment for patients with trochanteric region fracture and give the scientific community more evidence which methods is better since there is still controversy.

NCT ID: NCT03848195 Completed - Hip Fractures Clinical Trials

Hip Fracture in Individuals Under 60 Years of Age

HFU-60
Start date: July 29, 2015
Phase:
Study type: Observational

This study prospectively analyses and describes a cohort of non-elderly hip fracture patients at four orthopaedic departments in two Scandinavian countries regarding epidemiology, treatment, Patient Reported Outcome Measures, functional outcome as well as clinical results.

NCT ID: NCT03845153 Completed - Bone Fracture Clinical Trials

Metformin Effect on Fracture Healing in Post-Menopausal Women

Start date: January 1, 2019
Phase: Phase 4
Study type: Interventional

study the effect of metformin drug on fracture healing of patients with high risk of delayed fracture healing or non-union and correlating this to serum irisin myokine level.

NCT ID: NCT03833414 Completed - Clinical trials for Distal Humerus Fracture

Does Surgical-approach Affect Outcome After Fixation of Intra-articular Fractures of Distal Humerus?

Start date: January 2010
Phase:
Study type: Observational

observational study at tertiary care hospital and level 1 trauma centre aiming to evaluate the difference between two common surgical approaches to distal humerus fracture fixation.

NCT ID: NCT03831009 Completed - Ankle Fractures Clinical Trials

Weight-bearing Radiographs to Evaluate Stability in Ankles With Isolated Weber Type B Fractures.

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

The investigators will conduct a prospective cohort study on the use of weight-bearing radiographs to evaluate stability in ankles with isolated, trans-syndesmotic (Weber type B) fibular fractures. Stable fractures will be treated conservatively using a functional brace, unstable fractures will undergo surgical fixation.

NCT ID: NCT03828240 Completed - Hip Fractures Clinical Trials

HIP Fracture REhabilitation Programme for Elderly With Hip Fractures

HIP-REP
Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Objectives: To evaluate the feasibility of a HIP fracture REhabilitation Programme (HIP-REP).This study will investigate adherence, satisfaction, technical and practical circumstances regarding implementation and taking this into account when evaluating the feasibility of the HIP-REP program. Hypothesis: By testing the feasibility of a HIP-REP for the participants and the usefulness of the selected measurement tools, the investigators will be able to evaluate and adjust the HIP-REP before evaluating this in a larger Randomized controlled trial (RCT).