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Fractures, Bone clinical trials

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NCT ID: NCT04533984 Not yet recruiting - Stress Fracture Clinical Trials

Fracture Recovery for Returning to Duty (Teriparatide STRONG)

Start date: October 1, 2020
Phase: Phase 4
Study type: Interventional

FORTEO (teriparatide [rDNA origin]; Eli-Lilly, Indiana, USA) is an injectable synthetic recombinant human parathyroid hormone analog that is commonly used to treat people with osteoporosis. In the current investigation this drug will be tested to evaluate its efficacy to accelerate bone healing and decrease the convalescence time of US Army Basic Trainees who have sustained a diaphyseal tibial stress fracture (DTSF). Investigators from the University of South Carolina will collaborate with military personnel to perform a prospective, randomized, double-blind, placebo-controlled study at Fort Jackson, SC.

NCT ID: NCT04528264 Not yet recruiting - Clinical trials for Zygomatic Arch Fracture

Ultrasound Guided Closed Reduction of Depressed Zygomatic Arch Fractures

Start date: June 2021
Phase: N/A
Study type: Interventional

Zygomatic arch fractures have always been treated with blind closed reduction and is the most commonly used method. Blind reduction of fractures might lead to inadequate reduction and associated complications of facial asymmetry and limitations in mouth opening which may require reoperation for correction. Various methods like portable CT scan, C arm fluoroscopy, endoscopy and ultrasound have been proposed and used to visualize the reduction for better outcome. Out of these, ultrasound is inexpensive, easily available, easy to use, non-ionizing and has greatest potential to be used as standard for visual reduction of zygomatic arch fractures. There are studies where ultrasound has been compared to blind method and other modalities but level I evidence and recommended protocol for its intraoperative use has been lacking.

NCT ID: NCT04518839 Not yet recruiting - Quality of Life Clinical Trials

The Comparison of Cognition, Depression and Anxiety, and Quality of Life After Hip Fracture Surgery Under General or Regional Anesthesia

Start date: August 2020
Phase:
Study type: Observational

Postoperative cognitive dysfunction is a relatively common in elderly patients after hip surgery, but exact mechanism of its onset is still unclear as well as contributing factors. There is also increased incidence of depression and anxiety. Both affect the recovery after surgery, slow it down and reduce the quality of life. Patients will be divided into two groups, operated under regional anaesthesia and operated under general anaesthesia, and monitored after surgery. Patients will be tested before and after surgery to evaluate postoperative cognitive deficits, depression and anxiety scale and health-related quality of life questionnaire.

NCT ID: NCT04507880 Not yet recruiting - Shoulder Fractures Clinical Trials

A 2-Year Prospective Follow-up Study of the Global Unite Reverse Fracture Shoulder System for Proximal Humerus Fractures

Start date: August 1, 2020
Phase: N/A
Study type: Interventional

The objective of this study is to evaluated the efficacy and safety of the reverse total shoulder prosthesis (RTSA) for complex proximal humerus fractures. The clinical results of RTSA will be compared to clinical results from a historical cohort, that received a hemiarthroplasty of the shoulder.

NCT ID: NCT04473989 Not yet recruiting - Colles' Fracture Clinical Trials

Weekly Use of Teriparatide to Accelerate Healing of Distal Radius Fracture

Start date: June 1, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to examine the effect of weekly dosing strategy on fracture healing.

NCT ID: NCT04408053 Not yet recruiting - Clinical trials for Femoral Neck Fractures

Mini-invasive Preventive Fixation of the Contralateral Femoral Neck in Patients Operated on for a Femoral Neck Fracture

PREFIX
Start date: September 1, 2020
Phase: Phase 3
Study type: Interventional

In France, the annual incidence of hip fracture is about 80 000 with more than 75% of these fractures occurring in patients aged 80 years old or more. About 10% percent of patients presenting with a hip fracture will sustain a contralateral hip fracture, most within 3 years. The consequences of a hip fracture are dramatic: 20% of patients die in the first year and less than half those who survive regain their previous level of function. Hip fractures are invariably associated with chronic pain, reduced mobility, disability, and an increasing degree of dependence. The efficacy of pharmacological treatments to prevent a contralateral hip fracture is marginal and postponed and compliance is known to be poor. Osteoporosis is associated with cortical thinning and trabecular bone loss. Therefore, the mini-invasive preventive fixation (MIPF) of the contralateral femoral neck is appealing. The effect is immediate and compliance is certain. Morbidity is minimal because it is performed during the same operation as the fixation of the femoral neck fracture. The main objective of this study is to determine whether the mini-invasive preventive fixation (MIPF) of the contralateral femoral neck in patients having a femoral neck fracture is superior to no fixation regarding the occurrence of a contralateral hip fracture within 3 years.

NCT ID: NCT04393571 Not yet recruiting - Acetabular Fracture Clinical Trials

The Utility of Mobile Based Patient Reported Outcome Measures in Patients With Acetabular Fractures: A Randomized Controlled Trial.

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Acetabular fractures are articular fractures involving the hip joint that needs anatomical reduction and a strict long follow up after fixation.

NCT ID: NCT04355208 Not yet recruiting - Anterior Teeth Clinical Trials

Shade Evaluation of Monochromatic Versus Polychromatic Layering Techniques Inrestoration of Fractured Incisal Angle

Start date: October 2020
Phase: N/A
Study type: Interventional

This clincl trial will be conducted to compare theShade Evaluation of Monochromatic versus Polychromatic layering techniques in restoration of Fractured incisal angle

NCT ID: NCT04306198 Not yet recruiting - Hip Fractures Clinical Trials

Helical Blade vs Lag Screw Fixation for Cephalomedullary Nailing of Low Energy Intertrochanteric Hip Fractures

Start date: March 2020
Phase: N/A
Study type: Interventional

The purpose of this study will be to compare the failure and complications rates of and orthopedic implant (Cephalomedullary Nail) fixed with two different options actually available: lag screw or helical blade. The study population will be patient who have been diagnosed with an intertrochanteric hip fracture. Hypothesis: Our hypothesis is that the helical blade will have a higher failure rate compared to the lag screw

NCT ID: NCT04298385 Not yet recruiting - Trauma Clinical Trials

Traction Orthosis for Oblique Proximal Phalangeal Fractures

Start date: March 2020
Phase:
Study type: Observational

The term Ligamentotaxis is used to define the method of distal traction to realign joint surfaces and reduce articular fragments after complex fractures. Traction and mobilization can be combined to help deliver the best outcome. This study will present a dynamic traction orthosis design with the aim that it is easy-to-make, non-invasive, low-profile and allow for ease in performing active and passive exercises. The clinical effectiveness of this method will be examined by analyzing treatment outcomes in a case series cohort.