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Fractures, Bone clinical trials

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NCT ID: NCT03599336 Terminated - Arthropathy Clinical Trials

RSA vs. Nonop for 3 & 4-Part Proximal Humerus Fractures

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

There is currently no consensus amongst orthopedic specialists on the best way to treat 3- and 4-part proximal humerus fractures. No surgery and surgery with a type of shoulder replacement called a reverse total shoulder arthroplasty are two options that many orthopedists use. This study is being performed to evaluate the differences in short- and long-term pain and functional outcomes between patients who are treated with these two different options.

NCT ID: NCT03598530 Active, not recruiting - Tibial Fracture Clinical Trials

Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures

FROST
Start date: April 4, 2019
Phase:
Study type: Observational [Patient Registry]

Approximately 1000 patients presenting with tibial shaft fractures (AO type 42) will be enrolled prospectively in this registry. All patients are treated and followed at 6 weeks, 6 months and 1 year postoperative always following the local standard of care (routine) visit schedule up to 36 months if required. Data collection includes patient and fracture details, treatment details, functional, clinical and patient-reported outcomes and anticipated or procedure- and implant-related adverse events (i.e. complications) and their corresponding treatment

NCT ID: NCT03596736 Completed - Clinical trials for Distal Humerus Fracture

Elbow Hemiarthroplasty Versus Total Elbow Arthroplasty for Irreparable Distal Humeral Fractures

Start date: January 19, 2011
Phase: N/A
Study type: Interventional

Distal humeral fractures can be difficult to treat, in particular when the joint surface is affected (intra-articular fractures). If rigid internal fixation with plates and screws can be obtained it is considered to be the treatment of choice. In elderly patients, poor bone quality (osteopenia) and fragmentation of the articular surface can make rigid internal fixation non-reliable or even impossible. Total elbow arthroplasty has been shown to be of value in this type of situation. Elbow hemiarthroplasty has been proposed as an alternative to total elbow arthroplasty. The theoretical advantages as opposed to total elbow arthroplasty are: no restriction in the weight allowed to be lifted, complications related to polyethylene wear debris are avoided as there is no polyethylene liner and there is no ulna component that can loosen. Wear of the native ulna and instability are potential complications of elbow hemiarthroplasty. The aim of this multicenter study is to test the hypothesis that elbow hemiarthroplasty gives better elbow function than total elbow arthroplasty for irreparable distal humeral fractures.

NCT ID: NCT03596060 Recruiting - Hip Fractures Clinical Trials

Regional vs General Anesthesia in Patients With Hip Fracture Under Treatment With Clopidogrel

Start date: October 20, 2017
Phase: N/A
Study type: Interventional

This study compares general to regional anesthesia concerning morbidity and mortality in patients older than or equal to 65 years old who receive clopidogrel and are to be submitted in hip fracture surgery. Half of participants will receive general anesthesia the first 48 hours and the other half will receive regional anesthesia after 5 days of the discontinuation of clopidogrel.

NCT ID: NCT03595397 Not yet recruiting - Clinical trials for Thoracic Epidural Analgesia, Fracture Ribs

Thoracic Epidural Analgesia in Multiple Traumatic Fracture Ribs

Start date: July 2018
Phase: N/A
Study type: Interventional

This work aims at comparing the analgesic effect of Thoracic Epidural Magnesium sulfate versus Fentanyl when added as adjuvants to Bupivacaine in patients with multiple traumatic fracture ribs.

NCT ID: NCT03588689 Completed - Pain Clinical Trials

Continuous Fascia Iliaca Block for Acute Hip Fractures

Start date: May 7, 2018
Phase: Phase 4
Study type: Interventional

Hip fractures are a major cause of morbidity and mortality in the elderly with over 30,000 hip fractures occuring in Canada annually and over 1300 in Saskatchewan. The estimated cost associated with hip fractures is over $600 million nationally and 28 million dollars in Saskatchewan. Hip fractures cause a great deal of pain and immobility and are mainly treated with surgical fixation. In the perioperative period, hip fracture patients are treated mainly with opioids and other adjuncts such as NSAIDS and acetaminophen. Opioid consumption in the elderly population can predispose to delirium and respiratory complications such as atelectasis, respiratory depression, and pneumonia. Fascia iliaca blocks have been shown to be an effective mode of analgesia for patients with hip fractures, but are underutilized for varying reasons including culture of practice, expertise with performing the block, and having a dedicated service to do so. This study aims to compare the efficacy of fascia iliaca blocks to standard treatment (opioids) in the management of pain in hip fracture patients with a particular focus on outcomes such as the incidence of delirium, respiratory complications, and length of stay in hospital. Our idea is that if we can reduce the amount of opioids these patients receive then they will have improved pain control, fewer respiratory complications, earlier time to mobilizing, and shorter hospital stays. As far as we are aware this relation has not been well studied.

NCT ID: NCT03587571 Terminated - Clinical trials for Malleolus Fracture, Lateral

Comparing Function, Pain and Return to Work in Conservative Versus Surgical Treated Stable Lateral Malleolar Fractures

Start date: May 1, 2018
Phase: Phase 4
Study type: Interventional

Ankle fractures are one of the most common fractures in adults resulting in hospital stays and inability to work. Instable or dislocated ankle fractures are mostly treated by surgery. Treatment of stable lateral ankle fractures is still discussed controversial. They can be treated conservatively as well as by surgery. Furthermore, optimal aftercare is part of on-going discussion in both groups. Goal of any treatment is a fast, good functional outcome with pain free patients at low overall costs. Long-term results in terms of osteoarthritis should be kept in mind. The investigators seek to compare conservative and operative treatment in stable lateral ankle fractures in a prospective, randomised trial. The hypothesis is that there is no difference between conservative and surgically treated stable lateral malleolar fractures regarding pain, function, and return to the workplace.

NCT ID: NCT03581669 Withdrawn - Elderly Clinical Trials

Acetabular Cerclage and Total Hip Arthroplasty in the Treatment of Acetabular Fractures in Elderly Patients.

jantjeVL
Start date: August 2014
Phase:
Study type: Observational

We want to present the outcome of complex multifragmented acetabular fractures in the elderly treated with acetabular cerclage and total hip arthroplasty.

NCT ID: NCT03577678 Completed - Bone Fracture Clinical Trials

New Prosthesis for Comminuted Fracture of Lateral Half of Clavicle

Prosthesis
Start date: August 5, 2018
Phase: N/A
Study type: Interventional

This study to evaluate the efficacy of new prosthesis in treatment of comminuted fracture of lateral half of the clavicle in adult female.

NCT ID: NCT03576599 Terminated - Clinical trials for Stress Fracture Foot

Intravenous Bisphosphonate in Stress Fracture Treatment -A Randomised Controlled Double Blinded Multicenter Trial

Start date: June 29, 2017
Phase: Phase 4
Study type: Interventional

The effect of an intravenous bisphosphonate (zoledronic acid) on healing and symptoms of stress fractures that do not respond to conservative/conventional treatment within 6 months, will be investigated.