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Fistula clinical trials

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NCT ID: NCT05061264 Completed - Infection Clinical Trials

Abdominal Wall Reconstruction With PVDF Mesh in the Setting of Active Infection

Start date: May 2016
Phase: N/A
Study type: Interventional

The use of synthetic mesh to repair infected defects of the abdominal wall remains controversial. This study aimed to evaluate the short-term outcomes of using PVDF mesh to treat infected abdominal wall defects in the elective setting.

NCT ID: NCT05059119 Completed - Clinical trials for Locally Advanced Cervical Cancer

Rectovaginal Fistula in Post-Radiotherapy Advanced Cervical Cancer Patients

Start date: September 1, 2020
Phase:
Study type: Observational

To investigate the associated risk factors of rectovaginal fistula

NCT ID: NCT05038605 Completed - Hemorrhoids Clinical Trials

Topical vs Oral Metronidazole After Benign Anorectal Surgery

Start date: January 24, 2020
Phase: N/A
Study type: Interventional

While some investigators found oral metronidazole to be effective in reducing pain after hemorrhoidectomy, other researchers did not find a significant analgesic effect of systemic metronidazole. On the other hand, topical application of metronidazole had more consistent favorable results as Ala et al documented a remarkable analgesic effect of topical metronidazole 10% after excisional hemorrhoidectomy which was in line with Nicholson and Armestrong who also concluded similar results. No previous study compared the analgesic effect of topical and oral metronidazole after anorectal surgery. Therefore, the present trial was conducted to compare the impact of oral versus systemic metronidazole on pain and recovery after surgery for benign anorectal conditions.

NCT ID: NCT05034939 Completed - Clinical trials for Arteriovenous Fistula Stenosis

FLEX Vessel Prep Prior to Angioplasty in Native Arteriovenous Fistulae (AVF)

Start date: September 2, 2021
Phase: N/A
Study type: Interventional

A prospective, multi-center, randomized (1:1) clinical study evaluating the FLEX Vessel Prep device plus percutaneous angioplasty (PTA) (study arm) vs PTA alone (control arm) for the treatment of obstructive lesions in the native arteriovenous dialysis fistulae.

NCT ID: NCT05028400 Completed - Glioma Clinical Trials

Intraoperative Laser Speckle Contrast Imaging to Assess Blood Flow During Neurosurgery

LSCI-NSURG
Start date: February 1, 2022
Phase: N/A
Study type: Interventional

Cerebral blood flow (CBF) is of paramount importance to human brain function, as the brain relies on a continuous blood supply to meet its energy needs. Blockage of a cerebral blood vessel during neurosurgery, even if transient and short-lived, may result in irreversible brain tissue damage (i.e. stroke) and loss of cortical function, if not identified quickly enough. Laser speckle contrast imaging (LSCI) has been demonstrated to provide the ability to visualize flow in vessels in real time and continuously without the need for contrast agents. In LSCI, the tissue of interest is illuminated with low power laser light at red or near infrared wavelengths and the light reflected from the tissue surface is imaged onto a camera. The resulting images are laser speckle patterns and a computer processes the images to produce speckle contrast images, which are images of the motion within the field of view (ie, blood flow). The purpose of this clinical investigation is to assess the usefulness and accuracy of LSCI compared to ICGA and/or FA during neurovascular surgery. LSCI videos will be recorded automatically intraoperatively in each patient before, during, and after ICGA and/or FA in the same surgical field of view to guarantee comparability of the methods.

NCT ID: NCT05018962 Completed - Clinical trials for Dialysis Access Malfunction

Recurrent Stenoses in Arteriovenous Fistula (AVF) for Dialysis Access: CuttIng ballooN angioplaSTy Combined wITh Paclitaxel drUg coaTed Balloon Angioplasty, an observatIONal Clinical Study

INSTITUTION
Start date: September 8, 2017
Phase: Phase 2
Study type: Interventional

To determine if cutting balloon angioplasty combined with DEB angioplasty provides a higher primary patency after treatment of recurrent stenoses compared with cutting balloon angioplasty or angioplasty using DEB alone in the venous outflow AVFs. For cutting balloon angioplasty in venous stenosis, the primary patency after 12 months is 55-60% (9,16) and in recurrent stenoses up to 48%(10). We hypothesise that DEB angioplasty after cutting balloon angioplasty leads to improved primary patency at 12 months.

NCT ID: NCT05017207 Completed - Pancreatic Fistula Clinical Trials

Clinically Relevant Pancreatic Fistula After Pancreaticoduodenectomy

Start date: August 1, 2021
Phase:
Study type: Observational [Patient Registry]

Patients who are diagnosed with periampullary cancer will be performed pancreaticoduodenectomy with 3 types of pancreatic-jejunal anastomosis reconstructions. The investigator will analysis the complication of pancreatic fistula about: the clinical symptoms, laboratory test changing, intra-operative morphology, the risk factors

NCT ID: NCT05014425 Completed - Pancreatic Fistula Clinical Trials

Risk Factors for Post Whipple Pancreatic Fistula

Start date: January 1, 2017
Phase:
Study type: Observational

Postoperative pancreatic fistula (POPF) following pancreaticoduodenectomy is considered a life-threatening complication. This study was designed to analyze the risk factors for development of such fistula in a tertiary care center (Al-Rajhi Liver Hospital/ Assiut University).

NCT ID: NCT05006586 Completed - Fistula;Rectal Clinical Trials

Rectovaginal Fistula Repair

Start date: September 15, 2020
Phase:
Study type: Observational

This study is a prospective evaluation of quality-of-life after rectovaginal fistula repair at our institution

NCT ID: NCT04989868 Completed - Clinical trials for Complication of Surgical Procedure

Effect of Trans-Nasal Afferent Loop Decompression on Post-Pancreaticoduodenectomy Pancreatic Fistula

Start date: August 6, 2021
Phase: N/A
Study type: Interventional

Postoperative pancreatic fistula (POPF) is a major complication and an important cause of mortality after pancreaticoduodenectomy (PD). Trans-nasal afferent loop decompression technique (TNALD) may reduce the rate of POPF based on our previous retrospective study. The aim of this open-label randomized controlled trial is to determine whether TNALD is a protective factor against the development of POPF after PD.