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Fistula clinical trials

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NCT ID: NCT03469609 Recruiting - Enterostomy Clinical Trials

Mucous Fistula Refeeding Reduces the Time From Enterostomy Closure to Full Enteral Feeds ("MUC-FIRE" Trial)

MUC-FIRE
Start date: June 18, 2018
Phase: N/A
Study type: Interventional

The primary objective of this study is to demonstrate that mucous fistula refeeding between enterostomy creation and enterostomy closure reduces the time to full enteral feeds after enterostomy closure compared to standard of care.

NCT ID: NCT03455881 Recruiting - Tracheal Stenosis Clinical Trials

Phenotypic and Genetic Assessment of Tracheal and Esophageal Birth Defects in Patients

TED
Start date: March 28, 2018
Phase:
Study type: Observational

The investigators propose a preliminary study performing exome sequencing on samples from patients and their biologically related family members with tracheal and esophageal birth defects (TED). The purpose of this study is to determine if patients diagnosed with TED and similar disorders carry distinct mutations that lead to predisposition. The investigators will use advanced, non-invasive magnetic resonance imaging (MRI) techniques to assess tracheal esophageal, lung, and cardiac morphology and function in Neonatal Intensive Care Unit (NICU) patients. MRI techniques is done exclusively if patient is clinically treated at primary study location and if patient has not yet had their initial esophageal repair.

NCT ID: NCT03414060 Recruiting - Obstetric; Injury Clinical Trials

Feasibility of the Menstrual Cup for VVF

FMCVVF
Start date: August 8, 2016
Phase: N/A
Study type: Interventional

This study examines the feasibility and acceptability of the vaginal menstrual cup for short-term management of vesicovaginal fistula (VVF) among 11 women seeking treatment at a health facility in Ghana. The repeated measures design utilizes a 2-hr pad test to compare urinary leakage with and without the insertable cup, a questionnaire on acceptability and perceived effect is administered and a clinical exam is completed. Subsequently, semi-structured interviews will be carried out with up to 24 additional women seeking treatment at a health facility in Ghana. Interviews will cover women's experiences of living with fistula, including strategies for coping with urinary incontinence and resulting stigma, as well as user acceptability to the intervention.

NCT ID: NCT03397381 Recruiting - Clinical trials for Chronic Renal Failure

Outcome of Arterio-venous Fistula for Adult Hemodialysis Patients in Assiut Governorate

Start date: January 20, 2018
Phase:
Study type: Observational

identification of the factors that affect the outcome of arteriovenous fistula in chronic renal failure patients that newly established regular dialysis in Assiut Governorate 1. To study the factors that influence the outcome of AVF 2. To evaluate the vascular complications of AVF as occlusion, rupture, aneurysmal dilation and hand ischemia

NCT ID: NCT03391687 Recruiting - Gastric Cancer Clinical Trials

Incidence of Pancreatic Fistula After Radical Gastrectomy

Start date: December 1, 2017
Phase: N/A
Study type: Observational

This study is designed to investigate the incidence of pancreatic fistula after radical gastrectomy in gastric cancer patients.

NCT ID: NCT03365089 Recruiting - Clinical trials for Hemodialysis Access Failure

Collateral Ligation in Failing Fistulas

CLiFF
Start date: May 14, 2018
Phase: N/A
Study type: Interventional

Arteriovenous fistulas (AVFs) for hemodialysis often fail to become usable due to failure to mature (FTM). The most common cause is narrowing of the artery or vein (stenosis). Another potential cause is the presence of collateral or side branch veins that steal blood flow from the main fistula channel. Some believe that occluding these veins might help maturation of those failing AVFs. To evaluate if this actually works, patients with FTM will be randomly assigned to side branch vein ligation (or not), and rates of AVF maturation of the two groups will be compared.

NCT ID: NCT03355508 Recruiting - Clinical trials for Arterio-venous Fistula, Puncture, Chronic Desease

Impact of the Arteriovenous Fistula Puncture Technique On the Hemodialysis Session For Patient and Caregiver

Start date: September 29, 2017
Phase: N/A
Study type: Interventional

40000 patients are hemodialysis each year in France . In the case of chronic care, 78% of patients have an arteriovenous fistula. In order to perform the hemodialysis session, 2 techniques of puncture of the fistula are possible: - Bevel puncture upwards then flipping the needle - or puncture bevel down. At present, there is no consensus or study on the technique of puncture fistula which generates different professional practices.

NCT ID: NCT03325582 Recruiting - Perianal Fistula Clinical Trials

MR Assessment of Perianal Crohn's Disease

MAP
Start date: April 21, 2017
Phase:
Study type: Observational

Perianal Crohn's disease (pCD) is the commonest form of fistulising Crohn's disease, with up to 38% of patients affected and with 30% of them experiencing recurring disease symptoms. Presence of fistula can lead to major morbidity due to cutaneous perianal abscess formation or drainage. To date, it is very difficult to quantify inflammation in patients with pCD due to the absence of reliable disease activity measurements. In addition to this, optimising therapies for pCD is quite challenging and may have a major impact on quality of life. Magnetic resonance imaging of pelvic is a standard examination for the anatomical evaluation of pCD which is significant in terms of surgical therapy and progress. The overall hypothesis is that newer MRI techniques such as magnetization transfer (MT), diffusion weighted image ( DWI) and dynamic contract enhancement (DCE) are better suited to measuring the inflammatory vs fibrotic burden in pCD. The aim of this project is to measure disease activity within pCD and luminal CD using MRI sequences before and after biological therapy

NCT ID: NCT03322488 Recruiting - Crohn Disease Clinical Trials

Fistulodesis Pilot Study for Closure of Perianal Fistulae

Start date: June 20, 2017
Phase: N/A
Study type: Interventional

In this pilot study a new surgical treatment approach for perianal fistulae, called Fistulodesis, is performed. The study aims to assess effectiveness, safety and tolerability of the Fistulodesis procedure. The investigators are aiming to include 20 patients with Crohn's disease and 20 patients without underlying Crohn's disease. It is an open label study with an anticipated duration from January 2017 to January 2020.

NCT ID: NCT03310905 Recruiting - Clinical trials for Transplant;Failure,Kidney

Abdominal Wall Transplant

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

The purpose of this protocol is to determine the safety and efficacy of abdominal wall transplantation as a treatment for the reconstruction of abdominal wall defects. Abdominal wall transplantation may be performed alone or in combination with another transplant.