Fertility Disorders Clinical Trial
Official title:
Non-invasive Detection of Male Infertility With FDG-PET/MRI (Spectroscopy and DWI)
The aim of the study is to examine the value of the new MRI techniques (spectroscopy and DWI), and FDG-PET in prognostication of male infertility.
The diagnostic workup of male infertility includes medical history, physical examination and semen analysis. In severe cases further workup includes testicular ultrasound, analysis of genes and hormones and in a few cases testicular biopsies are necessary. Ultrasound is the first choice of imaging, but new MRI and PET techniques can provide additional information. Research indicates that new MRI techniques can measure the activity of the testicular sperm cell production non-invasively and FDG-PET can measure the testicular metabolism with a radioactively marked glucose analog (FDG). These imaging modalities are combined in a PET/MRI and we wish to perform a PET/MRI in 10 men with normal sperm counts and 10 men with low sperm counts in order to evaluate whether a PET/MRI can distinguish testicles with and without sperm cell production. We hope that this new non-invasive technique can replace the need for invasive biopsies and will be able to target the harvesting of sperm cells in fertility treatment. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05634850 -
Evaluating the Usability of the Product Kinder System Trial, Home Based Hormone for In-Vitro Fertilization (IVF) Monitoring System.
|
||
Completed |
NCT03803228 -
Dual Ovarian Stimulation (DUOSTIM) for Poor Ovarian Responders
|
Phase 3 | |
Active, not recruiting |
NCT06053827 -
Natural Frozen Embryo Transfer (FET) vs Substituted Frozen Embryo Transfer (FET)
|
||
Recruiting |
NCT03480412 -
Second Step Protocol in Poor Ovarian Responder (POR)
|
||
Not yet recruiting |
NCT04606082 -
Human Chorionic Gonadotropin Versus Granulocyte Colony Stimulating Factor in Increasing Pregnancy Rate in ICSI
|
N/A | |
Not yet recruiting |
NCT04604054 -
The Effect of Granulocyte Colony Stimulating Factor Versus Human Chorionic Gonadotropin in Females With a History of RIF
|
N/A | |
Not yet recruiting |
NCT04589793 -
COaching Lifestyle Intervention for FErtility
|
N/A | |
Completed |
NCT06441409 -
Serum Ferritin Levels and Metabolic Dysfunction Associated Steatotic Liver Disease
|
N/A | |
Completed |
NCT03846544 -
Double Pick up in Poor Prognosis Women
|
Phase 4 | |
Completed |
NCT04141436 -
Hypnofertility for Women Undergoing In Vitro Fertilization (HWUIVF)
|
N/A | |
Recruiting |
NCT05271981 -
Fertility After Uterine Artery Embolization
|
||
Completed |
NCT03007043 -
Genetic Variation in Gonadotropin and Gonadotropin Receptor Genes and Suboptimal Response
|
||
Completed |
NCT03161873 -
Cycle and Pregnancy Monitoring With Wearable Sensor Technology (AVA)
|
||
Completed |
NCT04133402 -
Fertility After Intrauterine Tamponing Balloon: Where Are we
|
||
Active, not recruiting |
NCT06128395 -
ASA 81 mg vs 162 mg During Frozen Embryo Transfer (FET)
|
||
Recruiting |
NCT05807256 -
Medically Assisted Fertilization Techniques in Systemic Immunoreumatologic Diseases
|
||
Completed |
NCT03908697 -
Quantum Natural Family Planning Pilot
|
N/A | |
Completed |
NCT04908774 -
Effects of a Fasting Mimicking Diet on Sperm Quality
|
N/A | |
Recruiting |
NCT05205733 -
Expanding Fertility Care to Poor and Low Resourced Settings Study
|
N/A | |
Active, not recruiting |
NCT03085212 -
Strategies for Pregnancy Achievement
|
N/A |