Clinical Trials Logo
  1. Home
  2. Fertility Disorders
  3. NCT03250195

Non-invasive Detection of Male Infertility With FDG-PET/MRI (Spectroscopy and DWI)

Fertility Disorders Clinical Trial

Official title:
Non-invasive Detection of Male Infertility With FDG-PET/MRI (Spectroscopy and DWI)

Clinical Trial Summary

The aim of the study is to examine the value of the new MRI techniques (spectroscopy and DWI), and FDG-PET in prognostication of male infertility.

Clinical Trial Description

The diagnostic workup of male infertility includes medical history, physical examination and semen analysis. In severe cases further workup includes testicular ultrasound, analysis of genes and hormones and in a few cases testicular biopsies are necessary. Ultrasound is the first choice of imaging, but new MRI and PET techniques can provide additional information. Research indicates that new MRI techniques can measure the activity of the testicular sperm cell production non-invasively and FDG-PET can measure the testicular metabolism with a radioactively marked glucose analog (FDG). These imaging modalities are combined in a PET/MRI and we wish to perform a PET/MRI in 10 men with normal sperm counts and 10 men with low sperm counts in order to evaluate whether a PET/MRI can distinguish testicles with and without sperm cell production. We hope that this new non-invasive technique can replace the need for invasive biopsies and will be able to target the harvesting of sperm cells in fertility treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03250195
Study type Interventional
Source Rigshospitalet, Denmark
Contact
Status Terminated
Phase N/A
Start date August 7, 2017
Completion date August 7, 2021
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05634850 - Evaluating the Usability of the Product Kinder System Trial, Home Based Hormone for In-Vitro Fertilization (IVF) Monitoring System.
Completed NCT03803228 - Dual Ovarian Stimulation (DUOSTIM) for Poor Ovarian Responders Phase 3
Active, not recruiting NCT06053827 - Natural Frozen Embryo Transfer (FET) vs Substituted Frozen Embryo Transfer (FET)
Recruiting NCT03480412 - Second Step Protocol in Poor Ovarian Responder (POR)
Not yet recruiting NCT04606082 - Human Chorionic Gonadotropin Versus Granulocyte Colony Stimulating Factor in Increasing Pregnancy Rate in ICSI N/A
Not yet recruiting NCT04604054 - The Effect of Granulocyte Colony Stimulating Factor Versus Human Chorionic Gonadotropin in Females With a History of RIF N/A
Not yet recruiting NCT04589793 - COaching Lifestyle Intervention for FErtility N/A
Completed NCT03846544 - Double Pick up in Poor Prognosis Women Phase 4
Completed NCT04141436 - Hypnofertility for Women Undergoing In Vitro Fertilization (HWUIVF) N/A
Recruiting NCT05271981 - Fertility After Uterine Artery Embolization
Completed NCT03007043 - Genetic Variation in Gonadotropin and Gonadotropin Receptor Genes and Suboptimal Response
Completed NCT03161873 - Cycle and Pregnancy Monitoring With Wearable Sensor Technology (AVA)
Completed NCT04133402 - Fertility After Intrauterine Tamponing Balloon: Where Are we
Not yet recruiting NCT04663971 - Fertility and Pregnancy After Surgery IBD Audit
Active, not recruiting NCT06128395 - ASA 81 mg vs 162 mg During Frozen Embryo Transfer (FET)
Recruiting NCT05807256 - Medically Assisted Fertilization Techniques in Systemic Immunoreumatologic Diseases
Completed NCT03908697 - Quantum Natural Family Planning Pilot N/A
Completed NCT04908774 - Effects of a Fasting Mimicking Diet on Sperm Quality N/A
Recruiting NCT05205733 - Expanding Fertility Care to Poor and Low Resourced Settings Study N/A
Active, not recruiting NCT03085212 - Strategies for Pregnancy Achievement N/A