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Fertility Disorders clinical trials

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NCT ID: NCT05489367 Enrolling by invitation - Fertility Disorders Clinical Trials

Does COVİD-19 m-RNA Vaccine Affect Fertility and Over Reserve ?

Start date: February 1, 2022
Phase:
Study type: Observational [Patient Registry]

Women's ovarian reserve and fertility were compared before and after 2 doses of vaccination

NCT ID: NCT05455281 Not yet recruiting - Fertility Disorders Clinical Trials

A Study to Evaluate the Performance of CHLOE Algorithm on the Prediction of Blastocyst Formation in Women Undergoing IVF [Cultivating Human Life Through Optimal Embryos]

CHLOE
Start date: July 2022
Phase:
Study type: Observational

This is an observational, prospective, single-arm, multi-center, clinical study to evaluate the performance of CHLOE, an Artificial Intelligence (AI)-based software application, as adjunct information to support identifying embryos on Day 3 that are most likely to form blastocysts.

NCT ID: NCT05448859 Completed - Fertility Disorders Clinical Trials

Effect of Oocyte Denudation Time and Intracytoplasmic Sperm Injection Time on Embryo Quality

Start date: January 1, 2017
Phase:
Study type: Observational

An observational analytic retrospective study was conduct using cross-sectional study. The subject were oocytes from in-vitro fertilization procedures using the ICSI method at the assisted reproductive technology clinic in a private hospital in Bandung for the period 2017 - 2019. Three variables were oocyte denudation time, ICSI time and embryo quality collected from samples that met the research criteria.

NCT ID: NCT05428124 Completed - Fertility Disorders Clinical Trials

Poor In Vitro Fertilisation Outcomes in Genital Tuberculosis - Case Report

Start date: January 1, 2014
Phase:
Study type: Observational

This is a case series that highlights the challenges in instituting in vitro fertilisation (IVF) treatment amongs genital tuberculosis patients.

NCT ID: NCT05412147 Not yet recruiting - Infertility, Female Clinical Trials

The Effect of RECO-18 on Infertile Women Undergoing in Vitro Fertilization-embryo Transfer

Start date: July 2022
Phase: N/A
Study type: Interventional

How to improve the fertility of infertile women has become a hot topic in the field of assisted reproduction. Animal experiment has shown that RECO-18 significantly improved the female fertility in mice, and the specific mechanism was related to reducing follicular atresia, promoting follicle development and improving oocyte quality. Therefore the investigators aim to conduct a pilot study to explore the effect of RECO-18 in infertile women undergoing assisted reproduction treatment. This study is a prospective, randomized, controlled clinical study. The treatment group takes RECO-18 while the control group takes the multi-vitamins. The primary indicator is the ongoing pregnancy rate at 12 weeks' gestation; the secondary indicators are the number of oocytes retrieved, the normal fertilization rate and the rate of high quality embryos, implantation rate, clinical pregnancy rate, and early miscarriage rate.

NCT ID: NCT05410314 Completed - Fertility Disorders Clinical Trials

Nutritional Supplement Based on Myo-inositol-D-chiro-inositoln in Long-term Survivors of Lymphoma

Linf-inositol
Start date: February 7, 2020
Phase:
Study type: Observational

The progressive improvement of lymphoma treatment has led to an important prolongation of patient survival and life expectancy. Therefore, the principal International scientific societies of oncology, recommend Long-term Survivors of Lymphoma to join fertility programs. Specifically, fertile age patients should be assisted by a multi-disciplinary team including specialists dedicated to fertility preservation in oncology, in order to support the completion of the reproductive project. In general population, the use of Inositol was spready considered an effectives choice to contrast ovarian dysfunction with consequently improvement of reproductive outcomes, so it may represent an adjuvant strategy for this purpose. Therefore, the investigators conducted a pilot study to evaluate the potentialities of this nutritional supplement with the aim to optimize the reproductive function in Long-term Survivors of Lymphoma. Despite the limited number of cases and short observational time, this pilot investigation could represent a potential cornerstone for further insights, discussions, and applications

NCT ID: NCT05409729 Recruiting - Fertility Disorders Clinical Trials

Subclinical Hypothyrodism and Ovarian Reserve

Start date: January 1, 2016
Phase:
Study type: Observational

This study aimed to evaluate the potential association of subclinical hypothyrodism and ovarian reserve in reproductive age in age groups more than 35 and age groups less than 35 using retrospective study included women with subclinical hypothyrodism and controls .Evaluation of potential association of antithyroid antibodies positivity on ovarian reserve Primary outcome: Measure the association of SCH with ovarian reserve markers (basal FSH ,LH/basal AFC /AMH)

NCT ID: NCT05271981 Not yet recruiting - Fertility Disorders Clinical Trials

Fertility After Uterine Artery Embolization

FERTI-EMBOL
Start date: April 1, 2022
Phase:
Study type: Observational

Uterine leiomyomas (or fibroids) are a common disease (30% of women over 35 years of age) in women of childbearing age and can cause various symptoms such as menometrorrhagia, dysmenorrhoea, pelvic pain and heaviness, and infertility. Uterine artery embolisation, first used in France in 1990, is a safe, effective and less invasive therapeutic technique than surgical treatment (myomectomy or hysterectomy), particularly in the case of numerous and large fibroids. This technique is validated by the French National College of Gynaecologists-Obstetricians (CNGOF) as an alternative treatment for women who do not wish to become pregnant (grade A recommendation), but at present there is little reliable data concerning fertility, the occurrence of pregnancy and the obstetrical prognosis after uterine artery embolisation for fibroids. A recent systematic review of the literature with meta-analysis published very recently showed that 40.5% of patients with a desire for pregnancy were able to become pregnant after embolisation (CI: 33.3%-48.2%) but that the rates of miscarriage, obstetric complications and low birth weight were not negligible (respectively 33.5% (95% CI: 26.3-41%), 25.4% (95% CI = 13-40.2%) and 10% (95% CI = 6.2-14.6%) (Ghanaati et al. 2020). In France, uterine artery embolisation is performed in more than thirty centres in women who have completed their parental project. On the other hand, in the absence of consistent literature, it is performed in patients of childbearing age, when it represents the only acceptable alternative or in the event of contraindication or refusal of surgery by the patient. To our knowledge, there is no large-scale French study to date on the impact of embolisation on fertility and pregnancy outcomes. The aim of this study is to compile a retrospective database of all cases of uterine artery embolisation for uterine pathology performed at the Georges-Pompidou European Hospital (HEGP) since 2007 and to assess the impact of embolisation on fertility in patients of childbearing age.

NCT ID: NCT05205733 Recruiting - Healthy Clinical Trials

Expanding Fertility Care to Poor and Low Resourced Settings Study

EXPLORE
Start date: May 24, 2022
Phase: N/A
Study type: Interventional

The investigators currently lack an understanding of barriers to completing the male factor infertility evaluation. Furthermore, as the investigators continue to expand access to fertility treatment particularly within low-resourced settings, it is important that all aspects of infertility within a couple are equally explored. The COVID-19 pandemic has disproportionately affected low-income communities and communities of color at greater rates in terms of not only disease morbidity/mortality but how medical systems are accessed and care is delivered.

NCT ID: NCT05164029 Not yet recruiting - Fertility Disorders Clinical Trials

The Clinical Cohort Study of Reproductive Health

Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

The study will conduct a multicenter prospective clinical cohort study to collect comprehensive health information and essential specimens from pre-pregnancy to postpartum offspring development. We will combine the reproductive medicine with the big data technologies and cloud computing to explore the key factors which will induce the occurrence the reproductive disorders and effect the health of women and offspring. Based on the discovery of the cohort study, we will construct a prediction model for improvement of ART,optimizing the effectiveness and safety of ART.