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NCT ID: NCT06159036 Completed - Female Clinical Trials

Effects of a Strength Training Program in Inertial Machines on Bosco Test in Youth Volleyball Players

Start date: September 26, 2022
Phase: N/A
Study type: Interventional

Objective: To determine the effect of strength training in inertial machines, on SJ CMJ and CMJ with arms; in youth volleyball players from the city of Cartago. Methodology: A quasi-experimental study of quantitative order was carried out and takes up an empirical-analytical approach, quasi-experimental with pre-test - post-test evaluation. 32 female volleyball players, belonging to the minor category of the Fénix G Club of the city of Cartago Valle Results: Both groups showed significant improvements in jump height, flight time, strength and power in the protocol that was carried out during the 12 weeks of intervention, but there was no statistically significant difference between the control groups (P = 0.356). , experimental (P = 0.984) Conclusions: Keywords: Inertial machines, Squat jump, Countermovent Jump, Abalakov

NCT ID: NCT06070064 Completed - Exercise Clinical Trials

Effects of Trap and Reggaeton Music on Movement Velocity, Power and Muscular Endurance in the Lower Limbs of Physically Active Women

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The influence of music on movement velocity and power during strength training have been poorly investigated, and specifically in women there is no evidence of an increase in strength performance due to the influence of music. Hypothesis: Listening to trap or reggaeton music will improve jumping ability, as well as movement velocity and power, muscular endurance, motivation and perception of effort in trained women during the performance of back-squats.

NCT ID: NCT05412459 Completed - Clinical trials for HER2-positive Breast Cancer

99mTc-DARPinG3-based HER2 Expression Molecular Imaging in HER2-positive Breast Cancer During Chemo+Targeted Therapy

Start date: May 1, 2022
Phase:
Study type: Observational

An open-label, single center study with 99mTc-DARPinG3 SPECT and biopsies of primary tumour in HER2-positive Breast Cancer in dynamic of chemo+targeted therapy, where the primary endpoint of the study is to find out the correlation between the HER2 expression measured by 99mTc-DARPin G3 SPECT and standard histopathology from primary tumor in dynamic of chemo+targeted therapy.

NCT ID: NCT05412446 Completed - Breast Cancer Clinical Trials

99mTc-ADAPT6 SPECT-based Non-invasive Quantification of HER2-expression in Breast Cancer With Metastatic Lymph Nodes

99mTc-ADAPT6
Start date: May 1, 2022
Phase: Phase 2
Study type: Interventional

An open-label, single center study with 99mTc-ADAPT6 SPECT and biopsies of primary tumour and metastatic lymph nodes in breast cancer patients, where the primary endpoint of the study is to find out the correlation between the HER2 expression measured by 99mTc-ADAPT6 SPECT and standard histopathology from relevant tumor and lymph node biopsies.

NCT ID: NCT05163236 Completed - Colonoscopy Clinical Trials

Sensitivity of Fecal Immunochemical Test (FIT) for Colorectal Cancer (CRC) Screening

FITBACK
Start date: April 20, 2021
Phase:
Study type: Observational

Fecal immunochemical test (FIT) was introduced in France late 2015, FIT has better diagnostic accuracy for colorectal cancers (CRCs) than previous screening tests. Our primary objective was to evaluate the sensitivity of FIT and the proportion of interval cancer.

NCT ID: NCT04561050 Completed - Bleeding Clinical Trials

Prediction of Massive Transfusion in Trauma Patients

MTP
Start date: August 1, 2020
Phase:
Study type: Observational

Since the 2000s, many prognostic scores were developed to predict traumatic haemorrhage. Most of these studies were retrospectives based on registers. Due to missing data on death due to bleeding, these studies chose to predict the massive transfusion risk as a surrogate of haemorrhagic death. These scores include clinical parameters (vital signs), laboratory values (Haemoglobin, lactate, Base excess) and/or imaging (CT or ultrasound) values. The scores showing best performance are the Trauma Associated Severe Haemorrhage (TASH) score, developed and validated on the German register (DGU-Register) and the ABC score developed and validated in the United States of America. However, the majority of these scores cannot be applied at the trauma scene due to the unavailability of laboratory and imaging values. Therefore, their clinical utility remains unclear. To overcome the need for diagnostic tests, authors have developed and recently validated a clinical prognostic score in identifying trauma patients with, or at risk of, significant haemorrhage based on predicted probabilities of death due to bleeding: BATT score. This score was developed from an international cohort using data from 271 Trauma Centres in 41 countries on 5 continents and uses first clinical parameters at initial assessment. The BATT score predicts death due to bleeding and has been validated on a large population in England and Wales. It could also predict massive transfusion, as a surrogate of haemorrhagic death, earlier at the trauma scene. Its feasibility and external validation would make its clinical utility superior to other scores while identifying a greater number of patients requiring early management. Our study is an external validation of pre-existing prognostic scores of traumatic haemorrhages (TASH , ABC and BATT score) at different times of care (Scene of Injury, admission at the trauma room) in order to assess their overall performance, discrimination and calibration in the prediction of massive transfusion, and haemorrhagic death. The objective of the study is to assess a comparison of score performances (Overall performance, discrimination and calibration). Due to the study population (STR), which is partly integrated into the German DGU-Register, the investigators expect good transportability of the TASH score to the Swiss Trauma Registry in terms of overall performance, discrimination and calibration. The ABC score should show lowers results in terms of discrimination due to its validation on small cohorts exclusively in North America. The new BATT score predicting death due to bleeding has been validated on a large English cohort of more than 100,000 patients. It identifies all patients with haemorrhage and not only patients who have received a massive transfusion subject to survival bias. In this context, the BATT score provides good discrimination with only simple physiological variables available at the trauma scene. In case of its external validation on the STR as part of our study, its feasibility would make its clinical utility superior to other pre-existing scores, while identifying a greater number of patients requiring early management. Its application would activate a massive transfusion plan directly at the trauma scene and save precious time.

NCT ID: NCT04555018 Completed - Acne Vulgaris Clinical Trials

Correlation Between Dehydroepiandrosterone Sulfate and Sebum Level in Adult Female Acne Vulgaris

Start date: June 1, 2017
Phase:
Study type: Observational

The aim of this study is to determine the correlation between Dehydroepiandrosterone sulfate (DHEAS) and sebum level in adult female acne. A cross sectional study was conducted with 50 samples, in June to October 2017.

NCT ID: NCT04524728 Completed - Neoplasm Malignant Clinical Trials

Patterns of Treatment and Outcome of Palbociclib Plus Endocrine Therapy

Start date: December 2016
Phase:
Study type: Observational [Patient Registry]

This is a multicentre real-world experience aimed at verifying the outcome of palbociclib plus ET in an unselected population of MBC patients. The primary endpoint is the clinical benefit rate (CBR); secondary aims are the median PFS (mPFS), overall survival (OS) and safety.

NCT ID: NCT04443231 Completed - Myopia Clinical Trials

Prospective Clinical Study of Retinal Microvascular Alteration After ICL Implantation

Start date: November 1, 2018
Phase:
Study type: Observational

To observe the retinal microvascular alteration during 3 months follow-up after Implantable Collamer Lens (ICL) operation in moderate and high myopia patients using quantitative optical coherence tomography angiography (OCTA) analysis.

NCT ID: NCT04436419 Completed - Obesity Clinical Trials

Immunometabolic Effects of Non-drug Strategies in the Clinical Management of Obesity: Translational Study

PPAR-NAPAS
Start date: July 2, 2018
Phase: N/A
Study type: Interventional

Forty women aged between 18 and 75 years-old with a BMI> 30kg/m2 are recruited to participate in the evaluation of their medical management. They participate in an 8-week protocol as part of hospital medical treatment for weight loss at the Oxford Polyclinic in Cannes (IPOCA). The effects of 2 independent variables will be studied: (1) an adapted physical activity program and (2) nutritional supplementation with R-α-Lipoic acid (2x300mg/d) versus placebo (double-blind). The volunteers are randomly assigned to the different groups: Placebo with or without exercise groups and ALA with or without exercise groups. At the start of the protocol (T0), at 4 weeks (T4) and at 8 weeks (T8), various measurements are carried out (physical capacities, nutritional status, body composition, distribution of adipose mass by CT-scan). A venous sample taken for all participants is done at T0, T4 and T8 to investigate the immune profile of circulating T lymphocytes. This project is part of a translational research project to assess current care and to investigate the immunometabolic effects of a non-drug medical care of obesity (adapted physical activities, nutritional supplementation with α-lipoic acid, quality of food intake).