Effect of Resistant Wheat Starch on Subjective Appetite and Food Intake in Healthy Adults

Feeding Behavior Clinical Trial

Official title:

Effect of Resistant Wheat Starch on Subjective Appetite and Food Intake in Healthy Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02689791
• Other study ID #: IowaSU
• Status: Completed
• Phase: N/A
• First received: February 7, 2016
• Last updated: February 18, 2016
• Start date: January 2012
• Est. completion date: August 2014

Study information

• Verified date: February 2016
• Source: Iowa State University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

A randomized, single-blind, cross-over study was conducted to determine the effect of replacing standard wheat flour (SWF) with resistant wheat starch (RWS) on markers of appetite and food intake in healthy adults.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 31
• Est. completion date: August 2014
• Est. primary completion date: January 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• BMI 18.5-29.9 kg/m2

• Regular breakfast consumers (>5 days/week)

Exclusion Criteria:

• not weight stable (?3 kg weight change in previous 3 months)

• use/used tobacco products

• presence of acute or chronic illness

• restrained eater (>13 on the restraint section of the three-factor eating questionnaire)

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject)

Related Conditions & MeSH terms

• Feeding Behavior

Intervention

Dietary Supplement:
• Resistant Starch Type 4
single dose 26g fiber given at the breakfast meal

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Iowa State University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Caloric intake	calories consumed at post-treatment lunch meal and total calories consumed on the treatment day	Single Day	No
Secondary	Visual analogue scale measures of subjective appetite	0-100mm scale to assess hunger, fullness, thirst, desire to eat and prospective consumption	Single Day	No
Secondary	Serum concentrations of biomarkers of appetite	CCK, ghrelin, PYY3-36 and GLP-1	150 minutes	No
Secondary	Plasma concentrations of biomarkers of glycemic response	Glucose, Insulin, GLP-1	150 minutes	No