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Emergence Delirium clinical trials

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NCT ID: NCT03208452 Completed - Clinical trials for Agitation,Psychomotor

The Effect of Intraoperative Magnesium Sulfate Infusion on the Occurrence of Emergence Agitation

Start date: March 19, 2017
Phase: Phase 4
Study type: Interventional

This study designed to evaluate the correlation between the effect of intraoperative magnesium sulfate infusion and the incidence of emergence agitation after pediatric ophthalmic surgery

NCT ID: NCT03179293 Completed - Emergence Agitation Clinical Trials

Transition to Propofol After Sevoflurane Anaesthesia to Prevent Emergence Agitation

Start date: July 1, 2017
Phase: Phase 4
Study type: Interventional

The aim of this randomized double-blinded study is to determine whether transition to propofol for 3 min at the end of sevoflurane anaesthesia reduces the incidence of EA in children undergoing genito-urinary paediatric surgeries.

NCT ID: NCT03172182 Completed - Anxiety Clinical Trials

Perioperative Effects of Operating Room Virtual Tour

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

Preoperative anxiety is associated with adverse consequences such as emergence delirium, and postoperative behavioral changes. According to previous studies, providing information of anesthetic procedures helps to lessen preoperative anxiety. However, verbal explanation alone provides the limited effect, and the tour program of the operating room prior to surgery may not be possible for a number of hospitals due to organizational and financial reasons. Therefore, the virtual reality (VR) tour of the operating room may be an innovative and novel method to give children information about the preoperative process and to alleviate the preoperative anxiety. In this study, we intend to evaluate the effects of the operating room virtual tour on preoperative anxiety as well as emergence delirium and postoperative behavioral changes, in pediatric patients.

NCT ID: NCT03171740 Completed - Emergence Delirium Clinical Trials

Premedication With Intranasal Dexmedetomidine or Midazolam for Prevention of Emergence Agitation in Children

Start date: June 1, 2017
Phase: Phase 3
Study type: Interventional

Study where children will receive one premedication, either intranasal dexmedetomidine or oral midazolam, to reduce agitation on emergence of anesthesia. The hypothesis is that dexmedetomidine is superior but previous studies lack quality.

NCT ID: NCT03132701 Completed - Emergence Delirium Clinical Trials

The Effect of Magnesium Supplementation During General Anesthesia on the Quality of Postoperative Recovery in Children

Start date: June 8, 2017
Phase: N/A
Study type: Interventional

Evaluation of prevention of emergence delirium and analgesic effect of magnesium on children

NCT ID: NCT03131375 Completed - Blood Pressure Clinical Trials

Dexmedetomidine Reduces Emergence Delirium in Children Undergoing Tonsillectomy With Propofol Anesthesia

Start date: May 1, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

Dexmedetomidine (DEX) is safe and effective in reducing ED following sevoflurane anesthesia. The investigators intend to study the efficacy of DEX in reducing ED in children undergoing tonsillectomy with and without adenoidectomy using total intravenous anesthesia (TIVA) with propofol .

NCT ID: NCT03124303 Recruiting - Delirium Clinical Trials

Interventions for Postoperative Delirium: Biomarker-3

IPOD-B3
Start date: February 13, 2017
Phase:
Study type: Observational

The IPOD-B3 study aims to characterize the relationship between premorbid brain activity and postoperative delirium in patients undergoing major surgery. This is a expansion of the NeuroVISION Bolt-On study, NCT01980511.

NCT ID: NCT03062488 Completed - Pain Clinical Trials

Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery

Start date: October 3, 2017
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to compare the incidence of EA in pediatric patients undergoing minor ENT surgery under Sevoflurane and compare opioid-only based intra-operative analgesia to multi-modal analgesia consisting of opioid and IV acetaminophen or PO acetaminophen regimen using a validated and standardized EA measurement tool, the Pediatric Anesthesia Emergence Delirium (PAED) scale. The post operative pain scores will be measured in all patients by post-op recovery staff using FLACC Score/Wong-Baker FACES (patients 24 months up to 7 years of age) or Numeric Pain Score for patients 7 years of age. The pre-operative, surgery, anesthesia and post-operative staff will be all blinded.

NCT ID: NCT02999542 Not yet recruiting - Emergence Delirium Clinical Trials

Effect of Music on Emergence Delirium

Start date: January 2017
Phase: N/A
Study type: Interventional

The researchers are conducting a research study to see whether listening to music during an operation will have a positive effect on the way that children wake up from surgery/anaesthetic. It is a common phenomenon where children wake up unhappy, irritated and screaming (known as emergence delirium). Research have shown that music decreases anxiety and pain. The researchers want to see whether music can also influence a child's behaviour after emerging from anaesthesia. In other words whether they will be more calm and cooperative after listening to music while they are asleep during surgery. Should music have a positive effect, anaesthesiologists may use it in future to improve care of patients coming for surgery.

NCT ID: NCT02980549 Completed - Emergence Delirium Clinical Trials

How Common Are Sleep Disorders and Problems With Emergence From Anesthesia in Surgical Patients

Start date: April 2015
Phase: N/A
Study type: Observational

Emergence delirium (ED), also called emergence agitation or post-anesthetic excitement, is defined as a dissociated state of consciousness, occurring on awakening from general anesthesia, in which children exhibit psychomotor agitation, crying and thrashing and are not consolable for a period of time, usually 5-15 minutes. Emergence delirium is a common problem in pre-school children, with estimates of the incidence ranging from 10-70% of children in this age group. These children are agitated, seemingly unaware of their surroundings, and typically do not respond to parents or caregivers. They are therefore at risk for self-inflicted traumatic injury and complications secondary to disruptions of intravenous lines, surgical incisions, or drains. Children with ED typically require more resources in the postoperative period than children who do not exhibit ED. Predicting the likelihood of ED would allow for better allocation of resources in the post-anesthetic care unit (PACU). The peak incidence of ED in children occurs in the same age range at which the peak incidence of parasomnias (PS) occurs. The description of parasomnias is strikingly similar to the description of ED; the American Academy of Sleep Medicine defines parasomnias as "undesirable physical events or experiences that occur during entry into sleep, within sleep or during arousals from sleep." Parasomnias can be diagnosed using a sleep questionnaire. The purpose of this pilot study is to determine the incidence of ED and PS in our population, in order to determine the number of patients necessary to enroll in a larger study to either confirm or reject the hypothesis that ED and PS are correlated.