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Emergence Delirium clinical trials

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NCT ID: NCT03337672 Completed - Tonsillitis Clinical Trials

Comparison of Dexmedetomidine and Midazolam for Prevention of Emergence Delirium in Children

Start date: December 5, 2017
Phase: N/A
Study type: Interventional

Emergence delirium is a common complication in children after anesthesia. The incidence of emergence delirium is reported upto 50%. Prevention of emergence delirium in children is important not only for the patient safety but also for the satisfaction of the parents. Midazolam is the most commonly used medications for prevention of emergence delirium. However, it might lead to delayed awakening from anesthesia and respiratory depression. In this study, the investigators will evaluate whether dexmedetomidine can be effectively and safely administered for prevention of emergence delirium in children compared to midazolam.

NCT ID: NCT03332407 Completed - Sleep Disorder Clinical Trials

Does Preoperative Sleep Quality Affect the Postoperative Emergence Delirium in Children Undergoing Strabismus Surgery

Start date: May 2, 2017
Phase: N/A
Study type: Observational

Sleep is important in maintaining the physiological function of the human body. Recently several studies have reported that preoperative sleep quality is associated with postoperative emergence delirium (ED) The ED is a common in pediatric patients undergoing general anesthesia with sevoflurane, but studies on the association of sleep quality have been rare. The investigators, therefore, aimed to investigate the relationship between postoperative delirium and pre and postoperative sleep quality in pediatric patients receiving strabismus surgery through this study

NCT ID: NCT03330613 Recruiting - Emergence Delirium Clinical Trials

Emergence Delirium and Recovery Time in Children

Start date: November 15, 2017
Phase: N/A
Study type: Interventional

In this study, inhalation anesthesia procedure and intravenous anesthesia method will be compared in terms of emergence delirium and recovery time in children who are scheduled for dental treatment under general anesthesia.

NCT ID: NCT03330236 Completed - Delirium Clinical Trials

EEG - Guided Anesthetic Care and Postoperative Delirium

EMODIPOD
Start date: October 13, 2017
Phase: N/A
Study type: Interventional

The study is a prospective, double blinded, randomized and controlled parallel trial to investigate the effect of the anesthetic care guided by EEG monitor (SedLine) on postoperative delirium. EMODIPOD = Electroencephalography Monitoring tO Decrease the Incidence of PostOperative Delirium

NCT ID: NCT03328910 Withdrawn - General Anesthesia Clinical Trials

The Relationship Between the SPI and the Postop ED

SPI_ED
Start date: August 2018
Phase:
Study type: Observational

Surgical plethysmography index (SPI) is a device that can noninvasively monitor the balance between the nociception and ant-nociception using pulse photoplethysmographic amplitude (PPGA) and heart rate obtained through an oxygen saturation measuring device. SPI has recently been studied as a useful tool to monitor the stress response of patients due to surgery or anesthesia and to guide the appropriate use of analgesics/anesthetics. However, these SPI devices have been developed for adults and have not been studied in pediatric patients with relatively high heart rates, and no direct effects on post-operative arousal excitability have been reported.

NCT ID: NCT03291626 Active, not recruiting - Clinical trials for Postoperative Delirium

Postoperative Delirium: EEG Markers of Sleep and Wakefulness

Start date: October 16, 2018
Phase:
Study type: Observational

Postoperative delirium is a condition in which patients develop temporary difficulties in maintaining attention and thinking clearly. These new problems can appear after surgery and change throughout the day. This confusion can last several days. The overall purpose of this study is to measure brain activity during sleep and wakefulness to learn about their relationships to delirium after surgery. While participants may not feel like their normal self during the study, they are in the best position to help us learn how to improve the recovery of brain function and sleep in others having surgery. The investigators need to learn from those who have and have not become confused after their surgical procedure.

NCT ID: NCT03285243 Completed - Emergence Delirium Clinical Trials

Effect of Monochromatic Light on Incidence of Emergence Delirium in Children

Start date: November 3, 2017
Phase: N/A
Study type: Interventional

Emergence delirium/emergence agitation (ED/EA) is a behavioral phenomenon of unclear etiology consisting of short lived behavioral changes that can be both traumatic to families and pose a safety risk to patients and staff. ED is characterized by a variety of presentations, including crying, excitation and agitation, that occur during the early stage of recovery from general anesthesia, generally in the first 30 minutes. Emergence delirium occurs in children of all ages following an anesthetic with halogenated agents (e.g. sevoflurane/isoflurane) with or without having undergone a surgical procedure (e.g. MRI patients). Presently, the treatment for ED is to revert the patient back to a hypnotic state mainly with sedatives so that they may "reset" themselves postulating that by re-inducing a hypnotic state, the brain has time to resolve this issue. The hypothesis of this study is that during ED, there is failure of organized EEG activity, especially alpha wave activity and that by enhancing alpha activity, the incidence of ED may be reduced without the need for additional pharmaceuticals which may be costly, delay recovery and are not without adverse effects specifically cardiopulmonary depression through the use of blue monochromatic light.

NCT ID: NCT03262090 Completed - Clinical trials for Ambulatory Surgical Procedures

Effect of Dexmedetomidine on the Prevention of Emergence Agitation in Children Undergoing Day Surgery

Start date: September 18, 2017
Phase: N/A
Study type: Interventional

Emergence agitation/delirium (EA/ED) is a common complication in pediatric surgery patients, which increases the risk of developing postoperative airway obstruction and respiratory depression. In infants, there is a high incidence of emergence agitation (EA) after desoflurane anesthesia. The aim of the present preliminary study was to determine the safety and efficacy of of intraoperative infusion of dexmedetomidine (DEX) that would prevent postoperative EA and ED in children undergoing day surgery with desoflurane anesthesia

NCT ID: NCT03252405 Completed - Emergence Agitation Clinical Trials

Effect of Induction Method in Post Operative Agitation

Start date: August 2, 2017
Phase: N/A
Study type: Interventional

To compare the effect of two different induction method; mask ventilation and intravenous cannulation on emergence agitation on pediatric adenotonsillectomy

NCT ID: NCT03229486 Completed - Emergence Delirium Clinical Trials

Effect of Sugammadex vs. Neostigmine/Glycopyrrolate on Pediatric Emergence Delirium in Sevoflurane-rocuronium Anesthesia

Start date: March 1, 2017
Phase: Phase 4
Study type: Interventional

The aim of this study is to investigate the effect of sugammadex vs. a conventional acetylcholinesterase inhibitor, neostigmine on emergence delirium (ED) during sevoflurane-rocuronium anesthesia in pediatric patients Additionally, the efficacy features of sugammadex compared to neostigmine will be examined by measuring the time from start of administration of reversal agents to recovery of train-of-four (TOF) ratio to 0.7, 0.8, and 0.9. Although the etiology of ED remains unclear, a sense of suffocation or breathing difficulty during emergence from anesthesia has been suggested as a possible cause. Thus, reversal of neuromuscular blockade with sugammadex in pediatric patients maintained with sevoflurane-rocuronium anesthesia may decrease ED due to its faster reversal of neuromuscular blockade and decreased possibility of residual blockade.