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Emergence Delirium clinical trials

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NCT ID: NCT06467552 Recruiting - Clinical trials for Postoperative Delirium

Effects of Nutritional Support on Postoperative Delirium

Start date: June 2024
Phase: N/A
Study type: Interventional

This study is a prospective, single-center, randomized controlled trial to compare whether applying nutritional supplementation therapy before and after surgery in elderly patients aged 65 years or older undergoing non-cardiac surgery can reduce the incidence of postoperative delirium.

NCT ID: NCT06445153 Recruiting - Clinical trials for Postoperative Delirium

Digitalized Clinical Decision Support for the Prevention of Postoperative Delirium (POD)

Start date: June 3, 2024
Phase: N/A
Study type: Interventional

The project aims to improve patient safety, reduce barriers to the implementation of current guideline recommendations, reduce workload in clinics, increase efficiency in work processes and close gaps in care.

NCT ID: NCT06426953 Recruiting - Diabetes Clinical Trials

Predictive Effect of TGF-β Combined With INS-PI3K-AKT Signaling Pathway Related Proteins (ADNP, MAP6, Pgc-1α) for POD on Diabetes Patients

Start date: May 20, 2024
Phase:
Study type: Observational

To investigate the relationship between POD, TGF-β and INS-PI3K-AKT signaling pathway related proteins (ADNP, MAP6, PGC-1α) in diabetic patients

NCT ID: NCT06421090 Recruiting - Clinical trials for Vagus Nerve Stimulation

Transauricular Vagal Nerve Stimulation Improves Postoperative Delirium in Elderly Patients

Vnstar-IIa
Start date: May 21, 2024
Phase: N/A
Study type: Interventional

To investigate the efficacy and safety of perioperative Transauricular vagal nerve stimulation in improving Postoperative Delirium in elderly patients undergoing elective surgery Lay the groundwork for a Phase III study.

NCT ID: NCT06421077 Recruiting - Clinical trials for Vagus Nerve Stimulation

Transauricular Vagus Nerve Stimulation Improves Postoperative Delirium in Elderly Patients

Vnstar
Start date: May 21, 2024
Phase: N/A
Study type: Interventional

According to the 3D-CAM scale, evaluate the incidence of Postoperative Delirium within 5 days after surgery in elderly patients receiving Transauricular vagal nerve stimulation.The results are expected to provide evidence of the safety and efficacy of perioperative prophylactic use of taVNS in the clinical application of improving postoperative brain health in elderly patients, as well as theoretical and practical basis for subsequent studies or clinical applications.

NCT ID: NCT06398275 Recruiting - Emergence Delirium Clinical Trials

Remimazolam for Emergence Delirium Prevention in Patients Undergoing Rhinoseptoplasty, FESS or Septoplasty

Start date: March 6, 2024
Phase: Phase 2
Study type: Interventional

The aim of this research is to confirm the effectiveness of remimazolam in preventing delirium during recovery from anesthesia in adult patients who have undergone one of the rhinological surgeries (septoplasty, rhinoseptoplasty or functional endoscopic sinus surgery). Patients aged 18-65, ASA classification I-II will be anesthetized with balanced anesthesia maintained with sevoflurane and will be randomized into two groups. The first group will receive remimazolam before anesthesia, while the second will receive normal saline solution. The main outcome of the study will be the presence/absence of delirium during anesthesia recovery, while the secondary outcome will be the postoperative pain level, the length of stay in the recovery room, the presence of unwanted events in the recovery room, and the presence of postoperative mood changes.

NCT ID: NCT06396468 Recruiting - Emergence Delirium Clinical Trials

Sevoflurane and Intravenous Anesthesia in Hypospadias Repair

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Emergence agitation (EA), a phenomenon observed at the time of recovery from general anesthesia (GA).The cause of ED appears to be multifactorial in origin. Use of volatile anesthetics, prolonged duration and type of surgery, pain, and rapid emergence are some factors known to increase its incidence

NCT ID: NCT06355570 Recruiting - Cardiac Surgery Clinical Trials

Delirium After Cardiac Surgery in Intensive Care Units

DaCsi-ICU
Start date: March 20, 2024
Phase: N/A
Study type: Interventional

STUDY SUMMARY STUDY DESIGN The study will be conducted over twelve months in the Cardiac Intensive Care Unit (ICU) at Hammersmith Hospital, Imperial College Healthcare NHS Trust (ICHT). This study is a mixed methods research design that includes the collection of data through qualitative interviews, quality-of-life questionnaires and patients' medical records. AIMS - Determine the incidence of ICU delirium in ICHT following cardiac surgery - Explore the compliance of outcome measures that diagnose ICU delirium - Implement a family-focused sensory stimulation programme in the ICU - Evaluate its useability and potential impact on patients, families and ICU staff STUDY POPULATION 30 study participants (12 patients, 12 family members/friends and 6 ICU nurses) ELIGIBILITY Study eligibility criteria are specific for each care group (patients, family members/friends and ICU nurses). DURATION 12 months at Hammersmith Hospital, ICHT

NCT ID: NCT06334939 Recruiting - Emergence Agitation Clinical Trials

Bispectral Index, Suppression Rate and Emergence Agitation in Spine Surgeries

Start date: January 1, 2024
Phase:
Study type: Observational

Emergence agitation; generally refers to a situation that may occur after a surgical intervention or anesthesia. This situation describes the irritability and agitation of the patient during the recovery process and the period of recovery from anesthesia. Recovery agitation may occur when the patient begins to recover and is usually a short-term condition. It resolves spontaneously. However, in some cases, this agitation may be more pronounced and disturbing. This may affect the patient's condition and relaxation. Rapid recovery from anesthesia in the clinic is also a risk factor for agitation. When the literature is examined, there are not enough studies on Bis suppression ratio and its relationship with recovery agitation is not yet known enough. For this purpose, our study aimed to question this relationship.

NCT ID: NCT06326983 Recruiting - Pain Clinical Trials

Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery

Start date: May 9, 2024
Phase: N/A
Study type: Interventional

This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham. The overall aim is to evaluate the efficacy of an opioid anesthetic plan (morphine, ketorolac, and acetaminophen versus an opioid sparing anesthetic plan (dexmedetomidine, ketorolac and acetaminophen) for perioperative analgesia and recovery time in patients undergoing tonsillectomies and tonsillotomies at Boston Children's Hospital Waltham. Secondary measures include rescue opioids administered in post-anesthesia care unit (PACU), re-operation secondary to bleeding, emergence delirium, post-operative nausea and vomiting, intraoperative hemodynamics, intraoperative vasopressor administration, and length of procedure.