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Embolism clinical trials

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NCT ID: NCT04795167 Completed - Clinical trials for PE - Pulmonary Thromboembolism

FLowTriever for Acute Massive Pulmonary Embolism (FLAME)

FLAME
Start date: March 16, 2021
Phase:
Study type: Observational

To evaluate treatment outcomes of patients diagnosed with high-risk (massive) pulmonary embolism

NCT ID: NCT04704349 Completed - Dementia Clinical Trials

Latest Imaging SPECT System Evaluation Phase 1

LISSE1
Start date: October 5, 2020
Phase: N/A
Study type: Interventional

Monocentric study for the evaluation of a whole body CZT scintigraphy system.

NCT ID: NCT04704258 Completed - Clinical trials for Aortic Valve Stenosis

NAUTILUS CE-mark Trial of the FLOWer Cerebral Embolic Protection Device

NAUTILUS
Start date: May 3, 2021
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to assess the safety, performance, and treatment effect of the use of the AorticLab FLOWer System, in preventing cerebral thromboembolic complications in patients with indication for a TAVI (Transcatheter Aortic Valve Implant).

NCT ID: NCT04702308 Completed - Pulmonary Embolism Clinical Trials

Non-Interruptive Alerts for Improving Use of Clinical Decision Rules

Start date: February 18, 2021
Phase: N/A
Study type: Interventional

This study is an extension of a planned quality improvement project that aims to promote standard of care by increasing the use of evidence-based clinical decision rules amongst emergency medicine providers in the University of Utah Emergency Department. Patient-specific information from the EHR will be used to recommend the use of relevant clinical decision rules to emergency medicine providers at the point-of-care. These recommendations will be in the form of non-interruptive alerts with one-click access to the suggested decision rules through the MDCalc Connect EHR add-on application. Specific aims of the study are to determine if 1) patient-specific non-interruptive alerts increase the use of clinical decision rules amongst emergency medicine providers and 2) an increase in the use of clinical decision rules affects provider ordering habits.

NCT ID: NCT04688320 Completed - Clinical trials for Massive Pulmonary Embolism

Massive Pulmonary Embolism: Trial of Non-immunogenic Recombinant Staphylokinase VS Alteplase FORPE

Start date: December 15, 2020
Phase: Phase 3
Study type: Interventional

Objective: to evaluate the efficacy and safety of the Recombinant Non-immunogenic Staphylokinase with its single bolus administration in comparison with the bolus-infusion administration of the Alteplase in patients with massive pulmonary embolism

NCT ID: NCT04654156 Completed - Pulmonary Embolism Clinical Trials

Assessment of Contrast Enhancement Boost for the Direct Identification of Pulmonary Emboli in Thoracic CT Angiography

Start date: January 1, 2019
Phase:
Study type: Observational

Pulmonary embolism is a common cardiovascular disease and thoracic CT angiography is currently considered the gold standard for its non-invasive diagnosis. However, the diagnostic performance of CT angiography can be hampered by an insufficient enhancement of pulmonary arteries. Contrast Enhancement Boost (CE Boost) is a post-processing technique using an iodine density map to artificially improve pulmonary artery enhancement. This retrospective study compares standard CT-angiography images with CE Boost images to assess the potential improvement of diagnostic performance for the detection of pulmonary embolism.

NCT ID: NCT04632641 Completed - Atrial Fibrillation Clinical Trials

Suture Closure AFtEr VEIN Access for Cardiac Procedures (SAFE-VEIN) Trial

SAFE-VEIN
Start date: April 23, 2021
Phase: N/A
Study type: Interventional

Primary objective: To compare the safety and efficacy of closure strategies post venous access procedures. Hypothesis: We anticipate that the use of a venous closure device will decrease the time to hemostasis (TTH), time to ambulation (TTA) and time to discharge (TTD) compared to conventional methods of closure following venous access procedure.

NCT ID: NCT04574895 Completed - Pulmonary Embolism Clinical Trials

Using a Real-Time Risk Prediction Model to Predict Pediatric Venous Thromboembolism (VTE) Events

Start date: November 2, 2020
Phase: N/A
Study type: Interventional

The study will evaluate the effectiveness of a novel, real-time risk prediction model for identifying pediatric patients at risk for developing in-hospital blood clots (or venous thromboembolism [VTE]) based on data easily extracted from the electronic medical record. The study will assess whether using the risk percentages for developing VTE derived from the model increases the number of high-risk patients screened by the pediatric hematology team, which may may lead to an overall reduction in the number of pediatric VTEs seen at Monroe Carell Jr. Children's Hospital at Vanderbilt.

NCT ID: NCT04479540 Completed - Pneumonia, Viral Clinical Trials

Assessment of the Risk of Pulmonary Embolism and Coagulation Profile in Patients With COVID-19 Lung Disease

COVIDEP
Start date: May 26, 2020
Phase: N/A
Study type: Interventional

The current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is complicated by pneumonia (15 to 20% of cases) requiring hospitalization with oxygen therapy. Almost 20 to 25% of hospitalized patients require intensive care and resuscitation; half die. The main cause of death is acute respiratory distress syndrome (ARDS). However, some deaths have been linked to pulmonary embolism (PE). Recognition of PE is important because there is specific treatment to limit its own mortality. The identification of biological parameters of hemostasis predictive of thromboembolic disease is crucial in these patients. To evaluate the frequency of PE in the patients having to be hospitalized is to practice of a systematic thoracic angiography scanner in the patients having no contra-indication for its realization, as well as during hospitalization in patients deteriorating without any other obvious cause. The thromboembolic events and disturbances of the coagulation system described in patients with SARS-CoV-2 pneumonitis suggest that this viral infection is associated with an increase in the activation of coagulation contributing to the occurrence of thrombosis and especially from PE.

NCT ID: NCT04455529 Completed - Clinical trials for Embolic Stroke of Undetermined Source

Current Situation of Natural History, Diagnosis and Treatment in Inpatients With Embolism Stroke of Unknown Cause (ESUS)

Start date: September 1, 2016
Phase:
Study type: Observational

Evaluate the epidemiological characteristics, risk factors, clinical characteristics in patients with ESUS and their medication compliance and relapse within 1 year.