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Elderly Patient clinical trials

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NCT ID: NCT06345118 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Evaluate the Results of Fall Prevention in Older Adults With Type 2 Diabetes Mellitus

FallT2DMOLD
Start date: March 1, 2024
Phase: N/A
Study type: Interventional

.This randomized controlled clinical trial aims to evaluate the effects of fall prevention in older adults with type 2 diabetes mellitus. The main questions it aims to answer are: - Describe the current situation of falls, the risk of falls, and some related factors in elderly type 2 diabetic patients - Evaluate the results of fall prevention and related factors in the study population. Participants will be randomly divided into control and intervention groups. The intervention group will be trained to follow the Otago Training Program as the primary fall prevention method. On the other hand, the control group will receive the standard care following the treatment guidelines for type 2 diabetes mellitus and other comorbidities. At the end of the intervention, the study will mainly compare the rate of fall incidents after 6 months of intervention as well as other physical performance tests.

NCT ID: NCT06340464 Recruiting - Cardiac Surgery Clinical Trials

Preoperative Nutritional Status Scores to Predict PPC in Elderly With Cardiac Surgery

Start date: March 21, 2024
Phase:
Study type: Observational [Patient Registry]

This prospective study investigate prognostic values and compare the role of nutritional status by using GNRI, MNA, and PNI in predicting post-operative pulmonary complication among elderly patients with cardiac surgery.

NCT ID: NCT05184166 Recruiting - COVID-19 Clinical Trials

Hospital Management and 1-year Outcome of Patients Aged 70 Years and Older With Severe COVID-19

ELDERCOV
Start date: January 4, 2022
Phase:
Study type: Observational

SARS-COV-2 infection can progress to acute respiratory distress syndrome and require hospitalization in the ICU in 5-20% of affected patients. Age is a major risk factor for developing a severe form and for death. ARDS related to SARS-COV-2 has specific features, including the need for long mechanical ventilation and length of stay and the use of corticosteroid therapy. These specificities are responsible for significant morbidity (neuromyopathy, delirium, post-resuscitation syndrome) and mortality during the first wave (46% at 3 months for the population of patients aged 70 years and over). To investigator's knowledge, no study has evaluated the prognosis in the ICU and the long-term functional outcome of elderly people admitted for a severe or critical form of COVID-19 since the major changes in management (dexamethasone, screening for thrombo-embolic complications, use of high-flow oxygen therapy as first-line treatment...). Investigator therefore propose a 1-year follow-up of a cohort of patients aged 70 and over hospitalised in a conventional service or in intensive care for a severe or critical form of COVID-19. The objectives are to describe the prognosis and functional outcome of hospitalized elderly patients with severe COVID-19.

NCT ID: NCT04580706 Recruiting - Clinical trials for Frail Elderly Syndrome

The Effect of Frailty and Other Geriatric Syndromes on the Prognosis of Elderly Patients With Acute Coronary Syndrome

Start date: January 1, 2020
Phase:
Study type: Observational [Patient Registry]

This is a prospective observational clinical trail which will recruit 1000-1500 participants over 65 years with frailty and acute coronary syndrome (ACS) in Beijing Friendship hospital. The investigators will conduct frailty assessment (FRAIL scale, CFS, SPPB), comorbidities, functional status (Barthel index, ADL, IADL), nutritional risk (MNA-SF), and then observe the clinical outcomes of elderly ACS participants with frailty. Then, the investigators will follow-up these participants separately in 1,3,6 and 12months, the anticipate follow-up time is 1 year. According to the follow-up results, investigators will evaluate the impact of frailty and other senile syndromes on the short-term and long-term prognosis of ACS, and develop a scoring system for the prognosis evaluation of elderly ACS participants.

NCT ID: NCT03705728 Recruiting - Clinical trials for Postoperative Delirium

Automated Administration of Intravenous Compared With Inhalatory Anesthesia on the Occurrence of Postoperative Delirium

AG-DPO
Start date: May 30, 2018
Phase: N/A
Study type: Interventional

The intravenous administration of anesthetic agents by a controller automatically-guided by an index of cerebral activity (i.e. the bispectral index) decreases the incidence of postoperative delirium, compared with an inhalational anesthesia.

NCT ID: NCT03375268 Recruiting - Complication Clinical Trials

Predictive Model for Postoperative Complications in Hemi-hip Arthroplasty

Start date: January 1, 2011
Phase: N/A
Study type: Observational

The purpose of this study was to identify the major complications and their risk factors of elderly patients who had undergone Hemi-hip Arthroplasty.

NCT ID: NCT01215604 Recruiting - Infection Clinical Trials

Involvement of Translation Initiation Factors in the Immune Response in the Elderly

Start date: October 2010
Phase: N/A
Study type: Observational

The investigators propose that the translation initiation factors eIF4E and eIF4GI may be involved in resolution of acute inflammation (regardless of age). Furthermore, the investigators suggest that differences in translation initiation factors state of activation may contribute to inflammation. Finally, the investigators hypothesize that differences in translation initiation factors state of activation may underlie the immune compromised state of the very elderly affording additional explanation for the heightened morbidity from infection in this group. In the current study the investigators aim to test these hypotheses by measuring the levels of eIF4E and eIF4G, their regulators, and targets in elderly (65-84yrs) and very elderly (85yrs<) patients hospitalized at Meir hospital for acute infection and after their recovery (detailed in study design).