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NCT ID: NCT06290219 Not yet recruiting - Effect of Drug Clinical Trials

The Effect of Platelet-rich Plasma Nasal Injection in the Treatment of Traumatic Olfactory Dysfunction

PRP
Start date: March 20, 2024
Phase: Phase 3
Study type: Interventional

The purpose of this study is to explore the efficacy of injecting high-concentration platelet plasma combined with hyaluronic acid into the nasal olfactory mucosa in the treatment of traumatic anosmia.

NCT ID: NCT06197295 Recruiting - Clinical trials for Urinary Bladder, Overactive

Efficacy of Combined Pharmacotherapy Versus Solifenacin With Vaginal Estrogen Cream for Women With Detrusor Overactivity

Start date: June 16, 2022
Phase: Phase 4
Study type: Interventional

To investigates the effects of combined pharmacotherapy with solifenacin and mirabegron versus solifenacin with vaginal estrogen cream in women with detrusor overactivity.

NCT ID: NCT06164821 Recruiting - Effect of Drug Clinical Trials

Clinical Observation of Luspatercept in Treatment of Chinese Adult β-thalassaemia Patients With TD β-thalassemia

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

To assesse the efficacy and safety of luspatercept versus placebo in China patients with transfusion-dependent β-thalassaemia.

NCT ID: NCT06141096 Recruiting - Safety Issues Clinical Trials

MB07133 for the Treatment of Patients With Unresectable Hepatocellular Carcinoma

MB07133
Start date: January 17, 2020
Phase: Phase 2
Study type: Interventional

A randomized, open, multicenter clinical trial design was adopted, planned to be conducted in three stages, with 91 participants expected to be included in the study to evaluate the efficacy, tolerance, and safety of different doses of MB07133 in the treatment of unresectable advanced primary liver cancer.

NCT ID: NCT06114758 Active, not recruiting - Clinical trials for Postoperative Complications

Comparison Effectiveness of Rectal Misoprostol & Intravenous Tranexamic Acid Reducing Hemorrhage in Myomectomy

Start date: September 1, 2023
Phase:
Study type: Observational [Patient Registry]

Fibroids are the most commonly encountered tumors in the female reproductive system. In patients, fibroids most often lead to abnormal uterine bleeding and the resulting anemia. In some cases, they can cause infertility or habitual abortions. Another complaint caused by fibroids is pain due to pressure and effects on adjacent organs. Very large fibroids can lead to abdominal swelling. Therefore, if a patient becomes symptomatic due to fibroids, myomectomy or, if necessary, hysterectomy is required. Because fibroids have a significant blood supply, there is a high risk of intraoperative bleeding and related complications. Additionally, the most common complication in these patients after the operation is bleeding. In many of these patients, intraoperative or postoperative blood transfusions are performed. If bleeding cannot be intervened early in these patients, hemodynamic instability, shock, coagulopathy, and, in the final stage, death can occur due to hemorrhage. Therefore, both intraoperative and postoperative bleeding control is of vital importance in patients undergoing myomectomy.

NCT ID: NCT06114641 Recruiting - Safety Issues Clinical Trials

Effectiveness & Safety of Ovine Enoxaparin Sodium to Originator Enoxaparin in Non-ST-Segment Elevation Acute Coronary Syndrome (NSTEACS) Patients: a Multicenter, Non-randomized, Open-label, Non-inferiority Trial

Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

The aim of this study is evaluating safety and effectiveness of Ovine Enoxaparin Sodium in Non-ST-Segment Elevation Acute Coronary Syndrome (NSTEACS) Patients

NCT ID: NCT06100510 Not yet recruiting - Effect of Drug Clinical Trials

PFA 100 Evaluation and Reference Interval HOACNY

Start date: November 2023
Phase: Phase 4
Study type: Interventional

The purpose of this research is to evaluate instrument functionality and develop a reference range of normal data by healthy volunteers.

NCT ID: NCT06000462 Not yet recruiting - Obesity Clinical Trials

The Effect of Dapagliflozin on Weight Loss in Obese Adults Without Diabetes

DAPA-ANDO
Start date: December 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to examine the effectiveness of a drug named dapagliflozin (tested drug) on weight loss in young adults aged between 18 and 40 years with obesity who are not diagnosed with diabetes. The main questions this study aims to answer are: - How much weight in average can people loose with the use of tested drug compared to 2 other comparator drugs: metformin and placebo (non-medicated pill)? - What is the effect of using tested drug on other parameters used to assess blood pressure, cholesterol and sugar levels, and mental health? - How frequent are the side effects from using the tested drug compared to the comparator drugs? Participants will go through a 6-month program of physical activity and diet and measure their weight progress. Those who do not achieve the target weight reduction will be randomly assigned to any of the three drug groups, either testes drug group, comparator 1 (metformin), or comparator 2 (placebo).

NCT ID: NCT05968885 Recruiting - Clinical trials for Urinary Bladder, Overactive

Evaluation the Efficacy Between Botox Injection and Combination Pharmacotherapy in Patients With Detrusor Overactivity

Start date: October 1, 2021
Phase: Phase 4
Study type: Interventional

To investigates the effects of botulinum toxin type A bladder injection compared to combined pharmacotherapy with Mirabegron and Solifenacin.

NCT ID: NCT05918146 Not yet recruiting - Effect of Drug Clinical Trials

Dextrose Therapy on Physical Therapy in Subdeltoid Bursitis

Start date: June 20, 2023
Phase: Phase 4
Study type: Interventional

Physical therapy and hypertonic dextrose prolotherapy are often used to treat subdeltoid bursitis. This study aims to investigate the effects of hypertonic dextrose injection on physical therapy through a double-blind, randomized study.