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Edema clinical trials

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NCT ID: NCT00427986 Terminated - Clinical trials for Diabetic Macular Oedema

Clinical Study of the Effect of Intravenous Galactose on Diabetic Macular Oedema

Start date: January 2007
Phase: N/A
Study type: Interventional

The purpose of the present study is to examine, if retinal swelling in diabetic patients can be reduced by an intravenous injection of galactose.

NCT ID: NCT00358423 Terminated - Clinical trials for Cystoid Macular Edema

The Effect of Macugen in Patients With Chronic, Post-Operative Cystoid Macular Edema

Start date: July 2006
Phase: Phase 1/Phase 2
Study type: Interventional

This research is being done to look at the effects of an experimental drug called pegaptanib (also called Macugen) for the treatment of swelling in the retina (the light sensitive tissue in the back of the eye) that can occur after cataract surgery. Swelling in the retina can lead to blurry vision. The only treatment available for this condition is eye drops that decrease swelling in the back of the eye, but eye drops may not decrease the swelling in everyone. We want to see if pegaptanib can decrease swelling in the retina and improve vision in patients with swelling after cataract surgery.

NCT ID: NCT00346983 Terminated - Clinical trials for Cystoid Macular Edema

Macugen to Prevent Worsening of Macular Edema Following Cataract Surgery in Diabetics

Start date: June 2006
Phase: Phase 1/Phase 2
Study type: Interventional

This research is being conducted to look at the effects of an intraocular drug (pegaptanib, also called Macugen) for the treatment of swelling in the retina (the light sensitive tissue in the back of the eye) that often occurs following cataract surgery in patients with diabetic eye disease. Swelling in the retina can lead to blurry vision, and Macugen may reduce this swelling. Eyedrops that decrease inflammation also may help to stop some of the swelling. We are testing this drug (pegaptanib) to see if it can decrease swelling in the retina and improve vision in patients with diabetes who are having cataract surgery.

NCT ID: NCT00305331 Terminated - Parkinson's Disease Clinical Trials

Domperidone as a Treatment for Dopamine Agonist-induced Peripheral Edema in Patients With Parkinson's Disease

Start date: March 2006
Phase: Phase 2
Study type: Interventional

The dopamine agonists, pramipexole (Mirapex) and ropinirole (Requip), are drugs that are used to treat symptoms of Parkinson's disease. However, these drugs can induce bothersome leg swelling or edema in about 20 percent of patients. The cause of this edema is unknown but may be secondary to stimulation of peripheral dopamine receptors in the kidney or blood vessels. We hypothesise that a peripherally acting dopamine receptor antagonist, will reduce edema in PD patients. This study will assess the effect of the peripheral acting dopamine D2 receptor antagonist, domperidone as a potential treatment for dopamine agonist-induced leg swelling.

NCT ID: NCT00143039 Terminated - Clinical trials for Fetal Growth Retardation

Amniotic Fluid Tandem Mass Spectrometry for Pregnancies Complicated by NIH and Severe Symmetrical IUGR

TandemMS
Start date: March 2006
Phase: Phase 1
Study type: Observational

The objective of this pilot study is to prospectively evaluate amniotic fluid of pregnancies complicated by non-immune hydrops and severe symmetrical intrauterine growth restriction by tandem mass spectrometry for inborn errors of metabolism.

NCT ID: NCT00114062 Terminated - Uveitis Clinical Trials

Study to Treat Uveitis Associated Macular Edema

Start date: September 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether denufosol tetrasodium (INS37217) Intravitreal Injection is well tolerated and has the potential to treat uveitis associated macular edema.