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Edema clinical trials

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NCT ID: NCT00969293 Terminated - Macular Edema Clinical Trials

Study to Assess the Safety and Tolerability of a Single Administration of FOV2302 (Ecallantide) in Patients With Macular Edema Associated With Central Retinal Vein Occlusion

FOV2302
Start date: September 2009
Phase: Phase 1
Study type: Interventional

The purpose of the study is to evaluate the safety and tolerability of a single administration of FOV2302 (ecallantide) in patients with macular edema associated with central retinal vein occlusion.

NCT ID: NCT00779142 Terminated - Clinical trials for Diabetic Macular Edema

Utility of Intravitreal Methotrexate in Diabetic Macular Edema Resistant to Conventional Therapies

Start date: September 2011
Phase: N/A
Study type: Interventional

It is well known that blindness is one of the most feared disabilities expressed by patients in the United States. Estimates of the economic impact of visual disability in the current population exceed 30 million US dollars in this country alone. The reasons for this figure are many; however age related macular degeneration (ARMD), diabetic retinopathy, glaucoma and uveitis are responsible for the majority of permanent visual disability and hence the costs in both quality of life and placing an economic burden on society. Research that may help reverse various abnormal biological responses that lead to or worsen clinical manifestations of diabetic retinopathy would be valuable.

NCT ID: NCT00768040 Terminated - Clinical trials for Diabetic Macular Edema

Efficacy of Aliskiren in the Treatment of Diabetic Macular Edema

Start date: September 2008
Phase: Phase 2
Study type: Interventional

To assess the efficacy of oral aliskiren as a therapy for diabetic macular edema

NCT ID: NCT00692614 Terminated - Macular Edema Clinical Trials

A Study of MK0140 in Diabetic Patients With Macular Edema (0140-001)

Start date: June 2008
Phase: Phase 2
Study type: Interventional

This study will evaluate the treatment effect of three doses of the I-vation TA implant (MK0140) in diabetic patients with clinically significant macular edema.

NCT ID: NCT00691522 Terminated - Clinical trials for PRIMARY MALIGNANT and METASTATIC BRAIN TUMORS

Imaging Study of XERECEPT® Treatment for Peritumoral Brain Edema (PBE)

Start date: November 2008
Phase: Phase 2
Study type: Interventional

This is a phase II, multicenter, open-label, imaging study of hCRF in the reduction of PBE in patients with primary malignant or metastatic brain tumors. Approximately 30 to 60 patients will be assigned to 1 of 3 treatment groups and receive study drug for up to 28 days

NCT ID: NCT00668785 Terminated - Macular Edema Clinical Trials

Intravitreal Ranibizumab to Treat Macular Edema After Panretinal Photocoagulation (Phase II)

Start date: March 2007
Phase: Phase 2
Study type: Interventional

This is a randomized, open-label Phase II study evaluating the safety and efficacy of intravitreally administered ranibizumab 0.5mg in subjects with Proliferative Diabetic Retinopathy experiencing post- Panretinal Photocoagulation (PRP) macular edema.

NCT ID: NCT00642226 Terminated - Macular Edema Clinical Trials

Combined Vitrectomy and Triamcinolone in Macular Edema Secondary to Branch Retinal Vein Occlusion (BRVO)

Start date: November 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether pars plana vitrectomy in combination with triamcinolone acetate is effective in the treatment of macular edema due to branch retinal vein occlusion.

NCT ID: NCT00571142 Terminated - Clinical trials for Diffuse Diabetic Macular Edema

Vitrectomy and Bevacizumab for Diffuse Diabetic Macular Edema

Start date: November 2007
Phase: Phase 3
Study type: Interventional

To Evaluate combined effect of vitrectomy and bevacizumab to stabilize retinal thickness and visual acuity in patients with diffuse diabetic macular edema and their relation to renal disease.

NCT ID: NCT00566761 Terminated - Macular Edema Clinical Trials

Treatment of Bevacizumab and Triamcinolone in Treatment or Macular Edema Secondary to CRVO

MECROV
Start date: June 2007
Phase: Phase 4
Study type: Interventional

Treatment of macular edema secondary to central retinal vein occlusion is more effective with combined therapy of bevacizumab and triamcinolone than bevacizumab alone.

NCT ID: NCT00505947 Terminated - Clinical trials for Diabetic Retinopathy

Treatment of Refractory Diabetic Macular Edema With Infliximab

Start date: July 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if treatment with infliximab improves macular edema which is refractory to laser photocoagulation in patients with diabetes.