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Dyspnea clinical trials

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NCT ID: NCT00410293 Completed - Heart Failure Clinical Trials

NT-proBNP in Acute Dyspnea: Effects on Treatment, Hospitalisation and Costs

Start date: December 2004
Phase: N/A
Study type: Interventional

Diagnostic uncertainty in patients with complaints of shortness of breath presenting to the Emergency Department of a hospital may delay treatment and proper care. In patients with shortness of breath due to heart failure increased plasma levels of NT-pro-B-type natriuretic peptide (NT-proBNP) can be demonstrated. The use of NT-proBNP as a biomarker for heart failure in patients presenting to the emergency department with dyspnea might improve care and reduce length of hospital stay. To investigate the effect of NT-proBNP testing on patient care and time to discharge the NT-proBNP test will be randomized. In patients in the study group, the NT-proBNP plasma level is determined at admission and the physician in charge will immediately receive the result of the test. In patients in the control group blood will be sampled but the physician will recieve no information on the NT-proBNP plasma level. In our study we will investigate the effect of introduction of NT-proBNP as biomarker for heart failure on treatment, time to discharge and costs.

NCT ID: NCT00338481 Completed - Lung Neoplasms Clinical Trials

"Red Morphine Drops" for Symptomatic Treatment of Dyspnoea in Lung Cancer

Start date: April 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to test whether "red morphine drops" applied in the mouth are superior to an equivalent amount of morphine applied as subcutaneous injection for the relief of breathlessness in terminal patients suffering from primary lung cancer or lung metastases.

NCT ID: NCT00327873 Completed - Dyspnea Clinical Trials

Palliative Oxygen for the Relief of Breathlessness

Start date: May 2005
Phase: N/A
Study type: Interventional

The main goal of this study is to establish the effectiveness of palliative oxygen in the context within which it is usually provided--relief of the sensation of breathlessness and improvement in quality of life for people with maximally-treated life-limiting illness.

NCT ID: NCT00289276 Completed - Heart Diseases Clinical Trials

FAST (Fluid Accumulation Status Trial)

Start date: November 2003
Phase: N/A
Study type: Interventional

Heart failure is a progressive disease that decreases the pumping action of the heart. This may cause a backup of fluid in the heart and may result in heart beat changes. Using very low electrical pulses that travel across the inside of the chest cavity, thoracic fluid status monitoring (OptiVolâ„¢) can measure the level of resistance to the electrical pulses, which indicates the level of fluid in the chest. The purpose of this study is to collect information related to fluid build up in the chest of subjects with heart failure.

NCT ID: NCT00234286 Completed - Pain Clinical Trials

Intervention to Improve Care at Life's End

BEACON
Start date: August 2005
Phase: N/A
Study type: Interventional

The BEACON trial (Best Practices for End-of-Life Care for Our Nations' Veterans) was a six-site implementation study to evaluate a multi-component, education-based intervention to improve the quality of end-of-life care provided in VA Medical Centers.

NCT ID: NCT00206830 Completed - Heart Failure Clinical Trials

SHORTness of Breath In the Emergency Department (SHORTIE)

Start date: April 2005
Phase: Phase 2/Phase 3
Study type: Interventional

SHORTIE is a two-phase study to determine the impact of the Triage Profiler S.O.B. (Shortness Of Breath) Panel on patient management, outcome, and cost.

NCT ID: NCT00143793 Completed - Dyspnea Clinical Trials

NT-proBNP and New Biomarkers in Patients With Dyspnea and/or Peripheral Edema

MANPRO
Start date: June 2005
Phase:
Study type: Observational

The objectives of this study are to: - Evaluate the sensitivity and specificity of NT-proBNP (N-terminal prohormone brain natriuretic peptide) and new biomarker measurements for the diagnosis of heart failure in patients with acute dyspnea and/or edema. - Determine the exact biomarker cut-off point(s) for the differentiation of healthy persons, patients with heart failure and patients with dyspnea of other origin. - Evaluate treatment costs in patients with dyspnea under special consideration of NT-proBNP measurement.

NCT ID: NCT00130611 Completed - Dyspnea Clinical Trials

B-type Natriuretic Peptide for Acute Shortness of Breath EvaLuation (BASEL) Study - Private Practice

Start date: January 2004
Phase: Phase 4
Study type: Interventional

Cost-effective management of heart failure and pulmonary disease is of paramount importance. Unfortunately, the rapid and accurate differentiation of heart failure from other causes of dyspnea in private practice is challenging. B-type natriuretic peptide (BNP) levels are significantly higher in patients with congestive heart failure as compared to patients with dyspnea due to other causes. As a simple, non-expensive assay easily applicable in private practice is available, rapid measurement of BNP might be very helpful in establishing or excluding the diagnosis of heart failure in patients presenting with acute dyspnea in private practice. The aim is to test the hypothesis that a BNP guided diagnostic strategy would improve the evaluation and management of patients presenting with acute dyspnea to physicians in private practice and thereby reduce total cost of diagnosis and treatment. The primary endpoint is total medical cost within 3 months.

NCT ID: NCT00067691 Completed - Breast Neoplasms Clinical Trials

Acupuncture for Shortness of Breath in Cancer Patients

Start date: November 2001
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether acupuncture is effective in relieving shortness of breath among breast and lung cancer patients.

NCT ID: NCT00053846 Completed - Clinical trials for Unspecified Adult Solid Tumor, Protocol Specific

Buspirone in Reducing Shortness of Breath in Patients With Cancer

Start date: November 2002
Phase: Phase 2/Phase 3
Study type: Interventional

RATIONALE: Buspirone may be effective in reducing dyspnea (shortness of breath) in patients with cancer who are undergoing chemotherapy. PURPOSE: Randomized clinical trial to study the effectiveness of buspirone in reducing shortness of breath in patients who are undergoing chemotherapy for cancer.