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Dyslipidemia clinical trials

View clinical trials related to Dyslipidemia.

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NCT ID: NCT00858221 Completed - Obesity Clinical Trials

Association of Genes to Resistance to Weight Loss in Obese Patients

Start date: August 2008
Phase: N/A
Study type: Observational

The overall goal of this study is to determine whether variations in the perilipin, and several other, genes would be a useful tool for physicians who are caring for morbidly obese patients to guide therapy. The main hypotheses to be tested is that sequence variations (polymorphisms) in the perilipin gene and several other obesity-related genes are associated with resistance to weight loss for obese individuals on energy restricted diets, potentially playing a role in the development of obesity related complications.

NCT ID: NCT00847197 Completed - Dyslipidemia Clinical Trials

A Study to Evaluate MK1903 in Patients With Dyslipidemia (MK1903-004)

Start date: June 2008
Phase: Phase 2
Study type: Interventional

This study will evaluate the lipid-modifying effect and tolerability of MK1903 when compared to placebo in patients with dyslipidemia who are not on a statin or other lipid-modifying therapy.

NCT ID: NCT00845637 Completed - Dyslipidemia Clinical Trials

Effect of Eggplant Extract on Lipid Profile During Fasting and Postprandial Period

Start date: March 2004
Phase: Phase 1
Study type: Interventional

The purpose of this study was to assess the effect of eggplant extract capsules on the lipid profile of healthy individuals after an oral lipid overload test in a randomized, double-blind, placebo-controlled clinical trial.

NCT ID: NCT00829348 Completed - Dyslipidemia Clinical Trials

Short Message Service (SMS) Impact on Patient Compliance Receiving Long Term Lipid Lowering Therapy With Statins

Start date: August 2006
Phase: N/A
Study type: Interventional

The objective of the study is to determine whether short text massages could be used successfully as a compliance aid and improve clinical outcomes in long term lipid lowering therapy.

NCT ID: NCT00816829 Terminated - Obesity Clinical Trials

Effect of Fenofibrate on Sleep Apnea Syndrome

Start date: September 2005
Phase: Phase 2
Study type: Interventional

Objectives: to investigate for the potential effect of fenofibrate on symptoms and biological changes associated with sleep apnea syndrome.

NCT ID: NCT00768274 Completed - Clinical trials for Cardiovascular Disease

Safety, Pharmacokinetic Study of RVX000222 in Healthy Subjects and Subjects With Low HDL Cholesterol

Start date: September 2008
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate an oral formulation of RVX000222 for safety, pharmacokinetic and efficacy in healthy subjects.

NCT ID: NCT00749788 Completed - Dyslipidemia Clinical Trials

Efficacy and Safety Study of JTT-302 in Subjects With Low HDL-C Levels

Start date: December 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effect of JTT-302 on the increase of High Density Lipoprotein-Cholesterol (HDL-C) levels when administered daily for four weeks in subjects with low HDL-C levels.

NCT ID: NCT00748852 Completed - Dyslipidemia Clinical Trials

Safety Study of JTT-302 in Subjects With Low HDL-C Levels

Start date: January 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety of JTT-302 when administered for eight or 12 weeks in subjects with low HDL-C levels and to determine the effect of JTT-302 on lipid parameters and CETP activity and mass.

NCT ID: NCT00746460 Completed - Obesity Clinical Trials

The Healthy Options Feasibility Study

Start date: June 2008
Phase: N/A
Study type: Interventional

The investigators hypothesize that having health care providers other than physicians within a "Groupe de Médecine de Famille" conduct cardiovascular risk assessments and teach lifestyle interventions to primary prevention patients will increase the likelihood that patients will adopt and maintain healthy lifestyles. These objectives will be supported by providing subjects with a cardiovascular risk profile estimating the subject's risk of cardiovascular disease and teaching them how to use the resources related to lifestyle changes available on the www.myhealthcheckup.com Web site.

NCT ID: NCT00728910 Completed - Dyslipidemia Clinical Trials

Combined Effects of Non-statin Treatments on Apolipoprotein A-I Up-Regulation (CENTAUR): A Feasibility Study

CENTAUR
Start date: June 2008
Phase: Phase 2
Study type: Interventional

The investigators propose to investigate if using a combination of medications that may improve cholesterol give additional benefit to that gained from the statin medication, Lipitor. It is recommended that patients who meet certain criteria for risk of heart disease take a statin medication to improve cholesterol and hopefully reduce risk of heart disease. The combination therapy will include Lipitor, Niaspan, and investigational medication (known as ABT335) in a class of drugs called fibrates. We are looking to see if and how these three medications together might improve risk factors for atherosclerosis and influence HDL cholesterol. The study will also look at the safety and any side effects that might be associated with this combination of medications.