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Dysarthria clinical trials

View clinical trials related to Dysarthria.

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NCT ID: NCT05497362 Completed - Stroke Clinical Trials

Non-invasive Brain Stimulation as a Treatment for Dysarthria Post-stroke

Start date: April 1, 2016
Phase: N/A
Study type: Interventional

The proposed study aimed to determine if tDCS can help post-stroke patients with dysarthria.

NCT ID: NCT05244603 Completed - Clinical trials for Hearing Loss, Sensorineural

Application of Ideal Binary Masking to Disordered Speech

Start date: December 1, 2021
Phase: Early Phase 1
Study type: Interventional

Dysarthria and hearing loss are communication disorders that can substantially reduce intelligibility of speech and the addition of background noise adds a further challenge. This proposal utilizes an established signal processing technique, currently exploited for improved understanding of speech in noise for listeners with hearing loss, to investigate its potential application to overcome speech-in-noise difficulties for listeners understanding dysarthric speech. Successful completion of this project will demonstrate proof-of-concept for the application of this signal processing technique to dysarthric speech in noise, and inform the development of an R01 proposal to perform a large-scale evaluation of the technology, and clinically meaningful implications, in a broad range of disordered speech types and severities.

NCT ID: NCT05146765 Completed - Clinical trials for Dysarthria as Late Effect of Stroke

Efficacy of a Digital Therapeutic for People With Dysarthria After Stroke

Start date: January 18, 2022
Phase: N/A
Study type: Interventional

This pilot trial will establish the feasibility of a new digitized speech rehabilitation developed for patients with post-stroke dysarthria. For this study, participants will be instructed to use the speech therapy app for 30 minutes to 1 hour per day over a 4-week period.

NCT ID: NCT04910581 Completed - Wilson Disease Clinical Trials

rTMS in Wilson Disease Dysarthria

WILSTIM2
Start date: January 23, 2023
Phase: N/A
Study type: Interventional

Wilson disease is a hereditary hepatic and neurological disease associated with copper accumulation. Neurological symptoms are of extra-pyramidal, cerebellar and dystonic origin. Dysarthria is one of the debilitating symptoms of Wilson disease poorly responsive to pharmacological treatment. The most common form is a dystonic hyperkinetic Dysarthria. Pathophysiology of dystonia is still not elucidated. Motor cortex hyperexcitability has been demonstrated in various forms of dystonia. Furthermore, rTMS inhibitory applied over motor cortex has been shown to transitory reduce dystonic symptoms in various forms of dystonia. In the present study, we investigate the effect of a single 1Hz 20-minutes inhibitory rTMS session applied over the motor laryngeal cortex on dyasarthria is the main kinetic dysarthria has been shown to be associated with inhibition of laryngeal motor cortex in Parkinson disease.

NCT ID: NCT04897711 Completed - Dysarthria Clinical Trials

Perceptual Training to Improve Listeners' Ability to Understand Speech Produced by Individuals With Dysarthria

Start date: April 26, 2021
Phase: N/A
Study type: Interventional

There exist very few effective treatments that ease the intelligibility burden of dysarthria. Perceptual training offers a promising avenue for improving intelligibility of dysarthric speech by offsetting the communicative burden from the speaker with dysarthria on to their primary communication partners-family, friends, and caregivers. This project, utilizing advanced explanatory models, will permit identification of speaker and listener parameters, and their interactions, that allow perceptual training paradigms to be optimized for intelligibility outcomes in dysarthria rehabilitation. This work addresses this critical gap in clinical practice and sets the stage for extension of dysarthria management to listener-targeted remediation-advancing clinical practice and enhanced communication and quality of life outcomes for this population.

NCT ID: NCT04780230 Completed - Stroke Clinical Trials

Non-invasive Brain Stimulation to Enhance Treatment of Dysarthria Post-stroke

Start date: December 21, 2020
Phase: N/A
Study type: Interventional

The proposed study aims to determine if transcranial direct current stimulation can enhance the effect of speech therapy in post-stroke patients with dysarthria.

NCT ID: NCT04520828 Completed - Clinical trials for Acquired Dysarthria (Finding)

Immediate Effects of Postural Repositioning on Voice Production Tasks in Seated Individuals With Acquired Dysarthria:

Start date: June 28, 2012
Phase: N/A
Study type: Interventional

To determine the effectiveness of a single 10-min postural repositioning session on the maximum phonation duration in individuals with acquired dysarthria.

NCT ID: NCT04222049 Completed - Cerebral Palsy Clinical Trials

Application of Vibration Wave Therapy to the Children Suffering From Cerebral Palsy and Tongue Spastic Dysarthria

Start date: July 15, 2019
Phase: N/A
Study type: Interventional

Vibration therapy is the widely used in many neurological disorders for different type of problems. Recently, it is being used by researchers for the betterment of motor disorders and muscle movements of the cerebral palsy patients and significant results are obtained. Investigators are conducting this research to explore that whether this therapy can have some effect on the Spastic Tongue Dysarthria of the Cerebral Palsy patients.

NCT ID: NCT04203615 Completed - Parkinson Disease Clinical Trials

Effect of Noninvasive Brain Stimulation on Hypokinetic Dysarthria in Parkinson's Disease

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

Hypokinetic dysarthria (HD) is common in Parkinson's disease (PD) patients and responds only partially to pharmacotherapy and surgery. The investigators will explore long-term effects of repetitive transcranial magnetic stimulation (rTMS) applied over right superior temporal gyrus, brain area known to be engaged in the feedback control of voiced speech. The project results will allow for the identification of potential therapeutic effects of rTMS as a tool that could contribute to the speech therapy of HD in PD patients. The results will also enhance our understanding of brain mechanisms underlying specific long-term effects of rTMS.

NCT ID: NCT03613038 Completed - Parkinson Disease Clinical Trials

A Systematic Investigation of Phonetic Complexity Effects on Articulatory Motor Performance in Progressive Dysarthria

Start date: July 15, 2017
Phase: N/A
Study type: Interventional

The goal is to improve the fundamental knowledge about articulatory motor performance in people with Lou Gehrig's disease (also known as ALS) and Parkinson's disease (PD), in order to develop more sensitive assessments for progressive speech loss, which may lead to the improved timing of speech therapies.