Intraoperative Radiation Therapy (IORT) in DCIS

Status Active, not recruiting

Clinical Trial Summary

The goal of this study is to examine the role of Intraoperative Radiotherapy (IORT) in Ductal Carcinoma In-Situ (DCIS) and to improve the understanding of the clinical, radiographic, and patient-related impact of adopting IORT.

Clinical Trial Description

With advances in technology and screening, the overdiagnosis and overtreatment of ductal carcinoma in situ (DCIS) have increased. Minimizing treatment toxicity and cost is a high priority area of research. Intraoperative Radiation Therapy (IORT)is a form of radiation where a single high dose of irradiation is applied to the tumor bed at the time of lumpectomy. Its use has not been previously studied in DCIS. Proposed advantages include decreased toxicity to adjacent tissue and organs, reduction in healthcare costs, and improved quality of life. The investigators hypothesize that IORT is a safe and patient-friendly alternative to whole breast irradiation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03216421
Study type	Interventional
Source	Columbia University
Contact
Status	Active, not recruiting
Phase	N/A
Start date	September 12, 2017
Completion date	December 31, 2029

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