Diabetes Mellitus Clinical Trial
Official title:
Risk of Malaria and Other Parasitic Infections in Individuals With Type 2 Diabetes With or Without Metabolic Syndrome in Cameroon.
Non-communicable diseases (NCDs) such as diabetes are increasing in countries where malaria transmission is common. This study aims to investigate the relationship between NCDs and parasitic infections in Cameroon. The investigators will assess the risk of malaria, as well as other parasitic diseases, in a prospectively followed group of adults with diabetes, compared with those without diabetes. Malaria parasites and intestinal worms will be tested using blood and stool collected at four time points during a one-year follow-up. In addition, this project will investigate how natural protection against malaria is affected by diabetes and other risk factors for heart diseases.
Status | Recruiting |
Enrollment | 400 |
Est. completion date | January 30, 2025 |
Est. primary completion date | December 30, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 21 Years and older |
Eligibility | Inclusion Criteria: Age 21 years and above with diagnosis of type 2 diabetes - Exclusion Criteria: pregnancy - |
Country | Name | City | State |
---|---|---|---|
Cameroon | Limbe Regional Hospital | Limbe |
Lead Sponsor | Collaborator |
---|---|
Karolinska Institutet | European Foundation for the Study of Diabetes, University of Dschang |
Cameroon,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | schistosoma infection | detected schistosoma eggs in stool or urine by microscopy r PCR | 1 year follow up | |
Other | strongyloides infection | Ab against S ratti detected by ELISA | 1 year follow up | |
Primary | asymptomatic malaria | malaria parasites detected by RDT/microscopy/PCR | 1 year follow up | |
Secondary | symptomatic malaria | any symptomatic malaria detected during the study period , defined as symptoms such as fever, headache, body ache and positive microscopy and/or RDT | 1 year follow up |
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