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Telocytes in Placental Tissues of Patients With Gestational and Pre-gestational Diabetes

Diabetes in Pregnancy Clinical Trial

Official title:
Telocytes in Placental Tissues of Patients With Gestational and Pre-gestational Diabetes

Clinical Trial Summary

Examining the expression of telocytes in the placental tissues and umbilical cord of patients with gestational or pregestational diabetes during pregnancy compared to control.

Clinical Trial Description

this is an observational study, patients with gestational or pre-gestational diabetes undergoing elective (pre-labour) Cesarean section will be asked to participate in the study. Samples of placenta and umbilical cord will be taken postpartum and will be fixed and examined using immunohistochemistry to measure abundance of telocytes in these tissues. another group of patients with non complicated pregnancies will be asked to join as a control. As the topic was never studied before, a pilot phase of 10 patients per group will be done followed by sample size collection based on SD of number of telocytes in each group. Diabetes patients will divided in 3 subgroups; Gestational diabetes and pre-gestational diabetes type 1 or 2. Each group will be further subdivided according to HBA1C level collected at the time of delivery into controlled or non controlled. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05305326
Study type Observational
Source Sohag University
Contact Amr O Abdelkareem, MD
Phone 00201001259562
Email amr.oth@med.sohag.edu.eg
Status Recruiting
Phase
Start date December 1, 2021
Completion date December 31, 2022
View Details
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