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NCT01342614 Clinical Trial

The Effect of Metformin on the Correlation Between Hyperinsulinemia and Hypertension

Diabetes Mellitus Clinical Trial

Official title:
The Effect of Metformin on the Correlation Between Hyperinsulinemia and Hypertension

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01342614
Other study ID # MET140
Secondary ID
Status Completed
Phase N/A
First received April 26, 2011
Last updated May 11, 2011
Start date May 2006
Est. completion date August 2009

Study information
Verified date November 2005
Source China-Japan Friendship Hospital
Contact n/a
Is FDA regulated No
Health authority China:Ethical Committee of the China-Japan friendship Hospital
Study type Interventional

Clinical Trial Summary

The objective of this study is to investigate the effect of metformin on the correlation between hyperinsulinemia and hypertension.

Recruitment information / eligibility
Status Completed
Enrollment 140
Est. completion date August 2009
Est. primary completion date August 2009
Accepts healthy volunteers No
Gender Both
Age group 20 Years to 65 Years
Eligibility Inclusion Criteria:

- 20 to 65 years of age, regardless of sex

- duration of hypertension was <5 years

- overweight or obesity, mild to moderate hypertension, receive no euglycemic agent or antiobesity drug

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• Fosinopril
Fosinopril group received fosinopril, 10mg, once per day.
• Metformin
Metformin group was treated with metformin hydrochloride, 500mg, three times per day

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
China-Japan Friendship Hospital

Outcome
Type Measure Description Time frame Safety issue
Primary Blood pressure measurement 8 weeks Yes
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