Diabetes Clinical Trial
Official title:
Corneal Endothelial Changes Associated With Phacoemulsification in Diabetes
Some studies indicated that the diabetic corneal endothelium is morphologically abnormal and may be at risk in any intraocular surgical procedure, while others showed no significant differences between diabetic and non-diabetic corneal endothelium.The purpose of this study is to investigate the differences in corneal endothelial cell density and morphology in diabetic patients and normal patients after phacoemulsification with intraocular lens implantation.To investigate if haemoglobin A1c can be used as a predictor of corneal endothelial cell changes after phacoemulsification.
Some studies indicated that the diabetic corneal endothelium is morphologically abnormal and
may be at risk in any intraocular surgical procedure, while others showed no significant
differences between diabetic and non-diabetic corneal endothelium.The purpose of this study
is to investigate the differences in corneal endothelial cell density and morphology in
diabetic patients and normal patients after phacoemulsification with intraocular lens
implantation.To investigate if haemoglobin A1c can be used as a predictor of corneal
endothelial cell changes after phacoemulsification.
Specular microscopy photos will be taken pre-. and 3 month postoperatively. Cellular
parameters will be compared between the two groups prior and post surgery. Clinical
significant difference is defined as 1 SD (300 cell/mm2)
;
Observational Model: Case Control, Time Perspective: Prospective
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