Diabetes Mellitus Clinical Trial
Official title:
Comparison of Ultrasound-Guided Axillary Brachial Plexus Block Properties in Diabetic and Non-diabetic Patients: A Prospective Observational Study
Background and objectives: The investigators performed this study to explore whether the
presence of diabetes mellitus (DM) would affect the outcomes of axillary brachial plexus
blocks (ABPBs) in patients undergoing elective forearm and/or hand surgery. The primary
hypothesis was that the sensory block duration would be delayed in diabetic patients.
Methods: After obtaining ethics committee approval and written informed consent, 71 patients
were enrolled to the study. Diabetic patients were included in Group DM and non-diabetics
were included in Group NODM. All received ultrasound-guided ABPBs with the mixture of 10 mL
lidocaine 2% and 20 mL bupivacaine 0.5%. Our primary outcome was sensory block duration, and
secondary outcomes were sensory and motor block onset times, motor block duration,
time-to-first-pain (numeric rating scale (NRS) ≥4), postoperative NRS scores and rescue
analgesic consumption (NRS) ≥4) through the postoperative first 2 days. All outcomes were
assessed by a blinded investigators.
Background and objectives: The impact of diabetes mellitus (DM) on the practice of
peripheral nerve block anesthesia was mostly investigated in animal researches, and effects
on human models are required to be clarified. The investigators performed this study to
explore whether the presence of DM would affect the outcomes of axillary brachial plexus
blocks (ABPBs) in patients undergoing elective forearm and/or hand surgery. The primary
hypothesis was that the sensory block duration would be delayed in diabetic patients.
Methods: After obtaining ethics committee approval and written informed consent, 71 patients
with American Society of Anesthesiologists (ASA) physical status I-III and aged between 40
and 75 years were enrolled to the study. Diabetic patients were included in Group DM and
non-diabetics were included in Group NODM. All received ultrasound-guided ABPBs with the
mixture of 10 mL lidocaine 2% and 20 mL bupivacaine 0.5%. Postoperatively, patients were
administered paracetamol as rescue analgesics, if numeric rating scale (NRS) was ≥4. Our
primary outcome was sensory block duration, and secondary outcomes were sensory and motor
block onset times, motor block duration, time-to-first-pain (numeric rating scale (NRS) ≥4),
postoperative NRS scores, and rescue analgesic consumption (NRS) ≥4) through the
postoperative first 2 days. All outcomes were assessed by a blinded investigators.
;
Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03743779 -
Mastering Diabetes Pilot Study
|
||
| Completed |
NCT03786978 -
Pharmaceutical Care in the Reduction of Readmission Rates in Diabetes Melitus
|
N/A | |
| Completed |
NCT01804803 -
DIgital Assisted MONitoring for DiabeteS - I
|
N/A | |
| Completed |
NCT05039970 -
A Real-World Study of a Mobile Device-based Serious Health Game on Session Attendance in the National Diabetes Prevention Program
|
N/A | |
| Completed |
NCT04507867 -
Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III
|
N/A | |
| Completed |
NCT04068272 -
Safety of Bosentan in Type II Diabetic Patients
|
Phase 1 | |
| Completed |
NCT03243383 -
Readmission Prevention Pilot Trial in Diabetes Patients
|
N/A | |
| Completed |
NCT03730480 -
User Performance of the CONTOUR NEXT and CONTOUR TV3 Blood Glucose Monitoring System (BGMS)
|
N/A | |
| Recruiting |
NCT02690467 -
Efficacy, Safety and Acceptability of the New Pen Needle 34gx3,5mm.
|
N/A | |
| Completed |
NCT02229383 -
Phase III Study to Evaluate Safety and Efficacy of Added Exenatide Versus Placebo to Titrated Basal Insulin Glargine in Inadequately Controlled Patients With Type II Diabetes Mellitus
|
Phase 3 | |
| Completed |
NCT05799976 -
Text Message-Based Nudges Prior to Primary Care Visits to Increase Care Gap Closure
|
N/A | |
| Completed |
NCT06181721 -
Evaluating Glucose Control Using a Next Generation Automated Insulin Delivery Algorithm in Patients With Type 1 and Type 2 Diabetes
|
N/A | |
| Recruiting |
NCT04489043 -
Exercise, Prediabetes and Diabetes After Renal Transplantation.
|
N/A | |
| Withdrawn |
NCT03319784 -
Analysis for NSAID VS Corticosteroid Shoulder Injection in Diabetic Patients
|
Phase 4 | |
| Completed |
NCT03542084 -
Endocrinology Auto-Triggered e-Consults
|
N/A | |
| Completed |
NCT02229396 -
Phase 3 28-Week Study With 24-Week and 52-week Extension Phases to Evaluate Efficacy and Safety of Exenatide Once Weekly and Dapagliflozin Versus Exenatide and Dapagliflozin Matching Placebo
|
Phase 3 | |
| Recruiting |
NCT05544266 -
Rare and Atypical Diabetes Network
|
||
| Completed |
NCT01892319 -
An International Non-interventional Cohort Study to Evaluate the Safety of Treatment With Insulin Detemir in Pregnant Women With Diabetes Mellitus. Diabetes Pregnancy Registry
|
||
| Completed |
NCT05031000 -
Blood Glucose Monitoring Systems: Discounter Versus Brand
|
N/A | |
| Recruiting |
NCT04039763 -
RT-CGM in Young Adults at Risk of DKA
|
N/A |