Diabetes Mellitus Clinical Trial
Official title:
Hypomagnesemia as a Risk Factor for Development of Metabolic Syndrome
Objective : to test the BP lowering-effect of oral magnesium supplementation, as magnesium
chloride (MgCl2) solution, 2.5 g daily, in uncomplicated hypertensive type 2 diabetic
subjects with decreased serum magnesium levels Design : Randomised double blind placebo
controlled trial. Setting : Outpatients with type 2 diabetes from Durango, city in northern
Mexico Subjects : 82 subjects between 40 and 75 years of age with type 2 diabetes serum
magnesium deficiency and uncomplicated hypertension.
Interventions : During 4 months the intervention group received 2.5 gr of magnesium chloride
(50 ml of a solution containing 50 gr of MgCl2 by 1000 ml of solution ). Controls received
inert placebo.
Main outcome measure: Change in blood pressure. Increase of serum magnesium Secondary
outcomes measures: Changes in lipid profile
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
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