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Effect of Two Different Doses of Dexmedetomidine Infusion in Morbidly Obese Patients

Anesthesia Clinical Trial

Official title:
The Effect of Two Different Doses of Dexmedetomidine Infusion on Oxygenation, Lung Mechanics, and Quality of Recovery in Morbidly Obese Patients: A Prospective Randomized Controlled Study

Clinical Trial Summary

Compare the effects of two different doses of dexmedetomidine infusion on oxygenation as a primary outcome and on lung mechanics, quality of recovery and perioperative analgesia as secondary outcomes in morbidly obese patients with restrictive lung disease undergoing abdominal surgery.

Clinical Trial Description

Dexmedetomidine is a selective α2 receptor agonist and has sympatholytic, analgesic, anti-inflammatory and sedative properties. Dexmedetomidine decreased dead space and improved both lung compliance and oxygenation in chronic obstructive pulmonary disease (COPD) patients undergoing lung cancer surgery. The effects of dexmedetomidine on oxygenation and lung mechanics had been investigated in obstructive lung disease, but there are little information about its effect in morbidly obese patients with restrictive lung disease . ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06018948
Study type Interventional
Source Tanta University
Contact
Status Completed
Phase Phase 4
Start date September 1, 2019
Completion date September 30, 2021
View Details
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