Profiling the Dynamic of Binge Eating Disorder (PRODY-BED) — PRODY-BED  

Depressive Symptoms Clinical Trial

Official title: Profiling the Dynamic of Binge Eating Disorder (BED): A Longitudinal Study Examining the Influence of Emotion Regulation, Executive Function, Eating Pattern on BED and Outcome (PRODY-BED)

Status Recruiting

Clinical Trial Summary

The goal of this observational study is to explore if different and specific profiles can be identified in adults with binge eating disorder (BED) depending on their additional eating pathology, emotion regulation and executive functions. The main questions it aims to answer are:

• Is there different and specific subgroups of patients with BED according to baseline profiles in emotion regulation, executive function and additional eating pathology (including restriction, chaotic eating, grazing and eating on external cues)?

• Are subgroups of individuals with BED (based on identified profiles) associated with outcome at end of treatment and follow-up?

• What is the trajectories in remission rates of specific symptom dimensions (eating disorder pathology, emotion regulation, executive function, and depressive symptoms) in individuals with BED and is there specific trajectory profiles in these dimensions?

• Is early changes in specific symptom dimensions (eating pathology, emotion regulation, executive function, or depression) associated with outcome of BED? Participants will be asked to fill in questionnaires before treatment as usual, 10 weeks into treatment, at end of treatment and at 6- and 12-month follow-up.

Clinical Trial Description

Binge eating disorder (BED) is a severe eating disorder characterized by recurrent episodes of binge eating, where control over eating is lost and huge amounts of food are eaten within a short period of time. Hence, weight issues are often inevitable and overweight is common, as are social, mental as well as physical problems.

The etiology of binge eating disorder is an interplay of neurobiological and environmental factors. Overall pathological eating, including grazing, external, emotional or restrictive eating, is associated with binge eating, and so is dysregulation in the reward center, impairment of executive functions and emotion regulation. The investigators suggest that it is possible to identify specific profiles driving binge eating, depending on the severity of these dimensions, and that these profiles might predict the outcome of treatment. The investigators also suggest that early change in general eating pattern, emotion regulation, and depressive symptoms is associated with binge eating outcome. These assumptions will be tested in a sample of adults in treatment for BED at one of three sites using questionnaires before, during and after treatment, incl. 6- and 12-month follow-ups. ;

Related Conditions & MeSH terms

• Binge-Eating Disorder
• Bulimia
• Depression
• Depressive Symptoms
• Eating Behavior
• Emotion Regulation
• Executive Dysfunction
• Feeding and Eating Disorders

• NCT number: NCT05726721
• Study type: Observational
• Source: Aarhus University Hospital
• Contact: Loa Clausen, PhD
• Phone: +4529119734
• Email: loaclaus@rm.dk
• Status: Recruiting
• Start date: July 3, 2023
• Completion date: May 31, 2026