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Effect of Psychedelic VR-augmented Therapy on Patients With Clinical Depression

Depression Clinical Trial

Official title:
Effect of Psychedelic VR-augmented Therapy on Patients With Clinical Depression

Clinical Trial Summary

Research has demonstrated that psychedelic compounds possess significant therapeutic potential for a variety of disorders, including depression. Despite these findings, the underlying mechanisms driving the therapeutic efficacy of psychedelics remain elusive. Furthermore, there exists a debate over the contribution of the subjective psychedelic experience to their therapeutic benefits. In this study, virtual reality (VR) is utilized as a tool to replicate the subjective experiences induced by psychedelics, aiming to explore their impact on depressive symptoms within a clinical sample. The primary objective of this research is to examine the influence of psychedelic-like phenomenology, as simulated through VR, on depressive symptoms. The study is structured into two distinct arms: the experimental condition features 'Psyrreal,' a VR experience designed to emulate psychedelic effects and the control condition which includes 'Routine Realms,' an analogous VR experience devoid of psychedelic elements. A third waiting list condition may be included, dependent on the availability of sufficient participants and resources. Additionally, the study seeks to identify and analyze various potential mediators that might underpin the therapeutic outcomes observed.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06174285
Study type Interventional
Source University of Tartu
Contact Karl Kristjan Kaup, MSc
Phone +372 5342 8489
Email kaup.kristjan@gmail.com
Status Recruiting
Phase N/A
Start date November 6, 2023
Completion date November 30, 2024
View Details
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