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Clinical Trial Summary

Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease, and depression and anxiety are among the most common comorbidities in RA patients, with a high prevalence rate. Epidemiological studies have found that joint deformities, severe pain, positive serum RF titers, as well as comorbidities such as hypertension, insomnia, pain, and fatigue are significantly associated with depression and anxiety in RA patients. Currently, clinical studies have found that the relief of depression or anxiety is one of the expected treatment goals for RA patients. Due to the unclear pathogenic factors of depression or anxiety in RA patients, there is a lack of effective clinical treatment options. Therefore, this study will use a "causal inference model" to identify possible "mediating variables" that may lead to the comorbidity of RA and emotional disorders through clinical investigation, aiming to improve the precision of treatment for physicians.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05892562
Study type Observational
Source Zhejiang Chinese Medical University
Contact Shate Xiang, Master's degree
Phone 15157147753
Email xiangshate@163.com
Status Recruiting
Phase
Start date December 15, 2022
Completion date July 15, 2023

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