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Clinical Trial Summary

The clinical study is a randomized (1:1:1), double-blind, placebo-controlled clinical study. Recruit patients with moderate to severe depression. After signing the informed consent, patients who meet the inclusion criteria will be randomly assigned to the ATP group (fluoxetine combined with ATP) or phosphocreatine group (fluoxetine combined with phosphocreatine) or control group (fluoxetine combined with 0.9% sodium chloride) to received treatment. Then accessed scale, cognitive function and brain function before treatment and at one, two, and four weeks after treatment to initially explore the safety and efficacy of ATP combined with fluoxetine to rapidly improves moderate to severe depression.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05431413
Study type Interventional
Source Nanfang Hospital, Southern Medical University
Contact Bin Zhang, MD & PhD
Phone 86-020-62786731
Email zhang73bin@hotmail.com
Status Recruiting
Phase Phase 2
Start date January 7, 2020
Completion date December 30, 2025

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