Depression Clinical Trial
Official title:
Prospective Cohort Study on the Incidence of Geriatric Syndromes Overlap in Patients With Hospital Admission Due to Hip Fracture
The overlap of depression and delirium as geriatric syndromes present in elderly patients with hospital admission due to hip fracture has been previously studied. Nevertheless, the relationships between these two clinical processes and other geriatric syndromes, especially malnutrition, have not been studied. For this reason, a prospective cohort study has been designed to know the differences in the incidence of geriatric syndromes during hospital admission due to hip fracture in patients with and without risk of malnutrition.
Status | Recruiting |
Enrollment | 506 |
Est. completion date | December 31, 2019 |
Est. primary completion date | August 31, 2019 |
Accepts healthy volunteers | |
Gender | All |
Age group | 70 Years and older |
Eligibility |
Inclusion Criteria: Patients =70 years admitted to the University Hospital of La Ribera (HULR) with the main diagnosis of hip fracture (ICD 9 820. **) that are going to be operated on. Exclusion Criteria: Life expectancy less than 3 months Dementia GDS 7 that prevents collaboration in the completion of the scale of Global Depression of Yesavage. |
Country | Name | City | State |
---|---|---|---|
Spain | Hospital Universitario de la Ribera | Alzira, | Kingdom Of Valéncia |
Lead Sponsor | Collaborator |
---|---|
Hospital de la Ribera |
Spain,
Downing LJ, Caprio TV, Lyness JM. Geriatric psychiatry review: differential diagnosis and treatment of the 3 D's - delirium, dementia, and depression. Curr Psychiatry Rep. 2013 Jun;15(6):365. doi: 10.1007/s11920-013-0365-4. Review. — View Citation
Radinovic KS, Markovic-Denic L, Dubljanin-Raspopovic E, Marinkovic J, Jovanovic LB, Bumbasirevic V. Effect of the overlap syndrome of depressive symptoms and delirium on outcomes in elderly adults with hip fracture: a prospective cohort study. J Am Geriatr Soc. 2014 Sep;62(9):1640-8. doi: 10.1111/jgs.12992. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Depression and delirium overlap | To evaluate the incidence of overlap between delirium and depression in patients with malnutrition compared to patients without malnutrition Measures: Prevalence of depression in admitted patients using Geriatric Depression Scale (GDS) of Yesavage. 15-items version. Range 0 to 15 points. Depression is considered with 7 or more points. Incidence of depression in admitted patients using Confusion Assessment Method (CAM). Range 0 to 4 points. CAM is considered positive for delirium with 3 points. |
"4 weeks" | |
Secondary | Hospital complications | To estimate : - Number of hospital complications (surgical wound infection, pneumonia, pressure sores, urinary tract infection, sepsis, Deep Venous Thrombosis, Pulmonary embolism) |
"4 weeks" | |
Secondary | Hospital length of stay (days) | Measured in days | "4 weeks" | |
Secondary | Functional recovery. | Functional Ambulation Categories scale (FAC). Range 0 to 5. Positive functional recovery 2 or more points. Barthel Index for Activities of Daily Living. Range 0 to 100. <20 points: total dependence. 20-35 points: severe dependence. 40-55 points: moderate dependence. = 60 points: mild dependence. 100 points: independence. The Lawton Instrumental Activities of Daily Living Scale. Range 0 to 8 Instrumental dependency 4 points or lower score |
"4 weeks" | |
Secondary | Survival | To estimate the difference in in-hospital mortality and at 12 months between both groups. | "1 year" |
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