Social Behavior in Depression

Depression Clinical Trial

— HLGDep  

Official title:

Social Behavior in Depression

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03414606
• Other study ID #: HLGdepression
• Status: Recruiting
• Phase: N/A
• First received: January 22, 2018
• Last updated: February 4, 2018
• Start date: February 1, 2017
• Est. completion date: March 1, 2018

Study information

• Verified date: February 2018
• Source: Beijing Normal University
• Contact: Yina Ma, Doctor
• Phone: +8613810258647
• Email: yma[@]bnu.edu.cn
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

In the project, investigators basically plan to test the difference in social behavior and social cognition between depressive patients and healthy individuals. To test this, investigators plan to use traditional or novel behavioral experiment paradigms to target various behaviors.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 25
• Est. completion date: March 1, 2018
• Est. primary completion date: February 16, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

• Age range between 18 and 60

• Education experience above high school

• Score for Hamilton's Depression Scale >=17

• Diagnosis of depression through Scid

Exclusion Criteria:

• Undergoing electric shock treatment in 3 months

• Excluding those who with bipolar disorder

• Excluding those who with postpartum depression

• Excluding those who with hysteria

Related Conditions & MeSH terms

• Depression
• Depressive Disorder

Locations

Country	Name	City	State
China	Huilongguan Hospital	Beijing

Sponsors (2)

Lead Sponsor	Collaborator
Beijing Normal University	Huilongguan Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prosocial behavior	The prosocial behavior will be assessed by conventional economic games, including dictator game, message game, and ultimatum game.	Baseline
Primary	Cognitive flexibility	Cognitive flexibility will be assessed by psychological cognitive paradigm, i.e. reversal learning paradigm. The participants will be asked to choose the item with high probability to win reward.	Baseline
Primary	Valuation of social information	The valuation of social information was measured by psychological paradigm, developed from animal studies, called "pay-per-view". The participants will be asked make decision about more social information or more monetary reward.	Baseline
Primary	Optimism bias	Participants will complete two sessions of life event estimation, i.e. estimating their likelihood of experiencing each event on a self-paced basis.	Baseline
Primary	Emotion recognition	After viewing a video, participants will be asked to judge the person's attitude in the video. Through this paradigm, investigators could test emotional bias in social interaction in depressive patients.	Baseline
Primary	Model-free & model-based tendency	Participants will be asked to complete a two-stage task, by choosing the stimuli with high probability to obtain reward.	Baseline