Intravenous Iron May Increase Depression Among Hemodialysis Patients

Depression Clinical Trial

Official title:

Intravenous Iron May Increase Depression Among Hemodialysis Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03157050
• Other study ID #: BN-13058
• Status: Completed
• Phase: N/A
• First received: May 16, 2017
• Last updated: May 16, 2017
• Start date: January 14, 2016
• Est. completion date: May 16, 2017

Study information

• Verified date: May 2017
• Source: Benha University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

the aim of this study is to assess whether increased ferritin after intravenous iron therapy will lead to increased prevalence of major depression among treated patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 112
• Est. completion date: May 16, 2017
• Est. primary completion date: May 15, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 19 Years and older

Eligibility

Inclusion Criteria:

1. age was above 19 years,

2. patient on maintenance hemodialysis,

3. patient had iron deficiency anemia (ferritin > 100 ng/ml)

Exclusion Criteria:

1. patient has history of depression or already using antidepressant medication,

2. Lack of ferritin level increase = 50% from baseline level before IV iron administration,

3. patient already on oral or intravenous iron supplement

Related Conditions & MeSH terms

• Anemia, Iron-Deficiency
• Depression
• Depressive Disorder
• Hemodialysis Complication
• Iron Deficiency Anemia

Intervention

Other:
• Intravenous iron therapy
each patient with iron def anemia received an IV syringe of iron sucrose 100 mg every dialysis session for 10 doses

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Benha University	New Jeddah Clinic Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in patient health questionnaire-9 score	change in patient health questionnaire-9 score before and after intravenous iron therapy	on day 0 of start of intravenous iron and 1 week after completion of intravenous iron