Depression Clinical Trial
— SECSOfficial title:
National Multicentric Study on the Predictive Factors for Suicidal Behavior During a Major Depressive Episode
This study aims at identifying predictors of suicidal behaviors in depressed subjects. Investigators will first compare demographic, clinical, and biological features of depressed recent suicide attempters (within one week) and depressed subjects without lifetime history of suicide attempt. Baseline risk factors for suicide will be used to predict the risk of attempting suicide during a one year follow-up. A thorough evaluation of these patients will allow to identify the factors associated with suicidal risk and develop a simplified risk score that could be used in clinical settings to improve our practice.
Status | Recruiting |
Enrollment | 2000 |
Est. completion date | March 2018 |
Est. primary completion date | March 2018 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion criteria: - >18 years old - Diagnostic Statistical Manuel IV (DSM IV) criteria for major depressive episode ( - Subject signs a non-opposition form - Able to understand the nature, purpose and methodology of the study - Affiliated with a French social security agency - Not planning to change residence within 12 months - Available by phone and / or email Specific inclusion criteria for the suicide group: - Admission to the hospital within 48 hours of the last suicide attempt. Specific inclusion criteria for emotional control group: - No history of lifetime suicide attempt suicide. Exclusion criteria: - Patients hospitalized for more than 7 days - Refusal to participate - Individual deprived of freedom (by judicial or administrative decision) - Individual protected by law (guardianship) - Subject to exclusion period in another protocol - Not affiliated to a social security agency |
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Screening
Country | Name | City | State |
---|---|---|---|
France | Montpellier University Hospital | Montpellier |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Montpellier | Centre Hospitalier Charles Perrens, Bordeaux, Centre Hospitalier Régional et Universitaire de Brest, Centre Hospitalier Universiatire La Conception, Marseille, Centre Hospitalier Universiatire Lyon, Centre Hospitalier Universitaire de Besancon, Centre Hospitalier Universitaire de Nimes, Créteil Hospital, Hôpital Saint Anne, Paris, INSERM U1061 Montpellier, University Hospital, Lille |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Suicide attempt during follow-up | Evaluation of the occurrence of a suicide attempt by the Columbia-Suicide Severity Rating Scale (C-SSRS ) | At one year | No |
Secondary | Depressive level | Measured by clinician with Inventory of Depressive Symptomotology (IDS-C 30) | At 3, 6 and 12 months after the inclusion | No |
Secondary | Depressive level | Measured with a self questionnaire Quick Inventory of Depressive Symptomatology (QIDS-RS) | At 3, 6 and 12 months after the inclusion | No |
Secondary | Anxiety | Measured with a self questionnaire the State-Trait Anxiety Inventory (STAI) | At 3, 6 and 12 months after the inclusion | No |
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT05777044 -
The Effect of Hatha Yoga on Mental Health
|
N/A | |
Recruiting |
NCT04680611 -
Severe Asthma, MepolizumaB and Affect: SAMBA Study
|
||
Recruiting |
NCT04977232 -
Adjunctive Game Intervention for Anhedonia in MDD Patients
|
N/A | |
Recruiting |
NCT04043052 -
Mobile Technologies and Post-stroke Depression
|
N/A | |
Completed |
NCT04512768 -
Treating Comorbid Insomnia in Transdiagnostic Internet-Delivered Cognitive Behaviour Therapy
|
N/A | |
Recruiting |
NCT03207828 -
Testing Interventions for Patients With Fibromyalgia and Depression
|
N/A | |
Completed |
NCT04617015 -
Defining and Treating Depression-related Asthma
|
Early Phase 1 | |
Recruiting |
NCT06011681 -
The Rapid Diagnosis of MCI and Depression in Patients Ages 60 and Over
|
||
Completed |
NCT04476446 -
An Expanded Access Protocol for Esketamine Treatment in Participants With Treatment Resistant Depression (TRD) Who do Not Have Other Treatment Alternatives
|
Phase 3 | |
Recruiting |
NCT02783430 -
Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease
|
Phase 2/Phase 3 | |
Recruiting |
NCT05563805 -
Exploring Virtual Reality Adventure Training Exergaming
|
N/A | |
Completed |
NCT04598165 -
Mobile WACh NEO: Mobile Solutions for Neonatal Health and Maternal Support
|
N/A | |
Completed |
NCT03457714 -
Guided Internet Delivered Cognitive-Behaviour Therapy for Persons With Spinal Cord Injury: A Feasibility Trial
|
||
Recruiting |
NCT05956912 -
Implementing Group Metacognitive Therapy in Cardiac Rehabilitation Services (PATHWAY-Beacons)
|
||
Completed |
NCT05588622 -
Meru Health Program for Cancer Patients With Depression and Anxiety
|
N/A | |
Recruiting |
NCT05234476 -
Behavioral Activation Plus Savoring for University Students
|
N/A | |
Active, not recruiting |
NCT05006976 -
A Naturalistic Trial of Nudging Clinicians in the Norwegian Sickness Absence Clinic. The NSAC Nudge Study
|
N/A | |
Enrolling by invitation |
NCT03276585 -
Night in Japan Home Sleep Monitoring Study
|
||
Terminated |
NCT03275571 -
HIV, Computerized Depression Therapy & Cognition
|
N/A | |
Completed |
NCT03167372 -
Pilot Comparison of N-of-1 Trials of Light Therapy
|
N/A |