Neural and Cognitive Mechanisms of Depression and Anxiety: a Multimodal MRI Study

Depression Clinical Trial

Official title:

Neural and Cognitive Mechanisms of Depression and Anxiety: a Multimodal MRI Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02888509
• Other study ID #: UESTC-chenhuafulab-002
• Status: Recruiting
• Phase: N/A
• First received: August 30, 2016
• Last updated: August 30, 2016
• Start date: June 2015
• Est. completion date: January 2017

Study information

• Verified date: August 2016
• Source: University of Electronic Science and Technology of China
• Contact: Huafu Chen
• Email: chenhf[@]uestc.edu.cn
• Is FDA regulated: No
• Health authority: China: Ethics Committee
• Study type: Observational

Clinical Trial Summary

To explore the neural and cognitive mechanisms of depression (including unipolar depression and Bipolar disorder) and anxiety using multimodal MRI techniques.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 150
• Est. completion date: January 2017
• Est. primary completion date: January 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 16 Years to 55 Years

Eligibility

Inclusion Criteria:

• Age range from 16 to 55 years old.

• All patients were interviewed by two experienced psychiatrists using the Structured Clinical Interview for DSM-IV (patient edition)

Exclusion Criteria:

• Schizophrenia, mental retardation or personality disorder, any history of loss of consciousness, substance abuse, serious medical or neurological illness.

• Subjects with contraindications to MRI

Study Design

Observational Model: Cohort, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Depression
• Depressive Disorder

Locations

Country	Name	City	State
China	School of Life Science and Technology, University of Electronic Science and Technology	Chengdu	Sichuan

Sponsors (1)

Lead Sponsor	Collaborator
University of Electronic Science and Technology of China

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Brain structural and functional changes in patients	Structure and function changes in patients will be assessed by Voxel-based morphometry analysis for structural changes, as well as Regional homogeneity, Amplitude of lowfrequency fluctuation, etc, for functional changes.	one time point	No