Depression Clinical Trial
Official title:
tDCS as Continuation Treatment to Sustain Remission After Electroconvulsive Therapy in Depression
While electroconvulsive therapy (ECT) in major depression is effective, high relapse rates
and cognitive side effects limit its long-term use. There is no consensus about optimal
continuation pharmacological treatments after a ECT course.
Adjunction of tDCS to pharmacological continuation treatment after ECT may decrease relapse
rates.
In a prospective, randomized, double blind, controlled, long-term study, investigators assign 40 depressed patients, in remission after ECT course associated to venlafaxine, with lithium adjunction after ECT course, either to tDCS or sham tDCS. Depressive symptoms and cognition were assessed after acute ECT after six months of continuation therapy. ;
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