Treatment of Conduct Problems and Depression

Depression Clinical Trial

Official title:

Treatment of Youth Comorbid Conduct Problems and Depression

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01267773
• Other study ID #: MH086606
• Status: Recruiting
• Phase: Phase 1
• First received: November 16, 2010
• Last updated: March 20, 2013
• Start date: August 2010
• Est. completion date: May 2013

Study information

• Verified date: March 2013
• Source: Rhode Island Hospital
• Contact: Jennifer C Wolff, PhD
• Phone: 4014443790
• Email: jwolff2[@]lifespan.org
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

Having both depression and conduct problems at the same time has been found to be associated with increased risk for the other and increased risk of negative outcomes. This study will develop an family based cognitive behavioral treatment protocol for youths with both conduct problems and depression, that will take be administered over the course of six months. Youth with comorbid conduct problems and depression will be assigned to the experimental condition or treatment as usual in a community care setting. The treatment manual will be revised as needed. Youth will be assessed before and after treatment to examine program potential. The goal of this research is to develop a more comprehensive outpatient treatment for youth with both conduct problems and depression.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 30
• Est. completion date: May 2013
• Est. primary completion date: May 2013
• Gender: Both
• Age group: 8 Years to 14 Years

Eligibility

Inclusion Criteria:

• 8-14 years old

• Diagnosis of ODD or CD

• Diagnosis of Depression

• Speaks English

Exclusion Criteria:

• Developmental/cognitive delays

• Substance dependence

• Psychotic disorder or symptoms

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Attention Deficit and Disruptive Behavior Disorders
• Conduct Disorder
• Depression
• Depressive Disorder
• Disease
• Oppositional Defiant Disorder

Intervention

Behavioral:
• Integrated Treatment

Locations

Country	Name	City	State
United States	Rhode Island Hospital	Providence	Rhode Island

Sponsors (2)

Lead Sponsor	Collaborator
Rhode Island Hospital	Brown University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Depression Symptoms	Change in depression symptoms from baseline to week 24 will be measured using the Children's Depression Inventory	baseline to week 24	No
Primary	oppositional symptoms	change in symptoms of oppositionality from baseline to week 24 will be measured using the Disruptive Behavior Disorders Scale	baseline to week 24	No