Depression Clinical Trial
Official title:
Measuring Response to Depression Treatment: A Study Comparing the Sensitivity of Multiple Outcome Measures to Change
The primary goal of this study is to compare a new symptoms rating questionnaire, called the Vancouver Semi-Structured Interview for Depression (V-SID), to the traditionally used questionnaires. The investigators predict that the V-SID will be more sensitive to patients' improvement than are traditional questionnaires.
Depression is sometimes associated with difficulties in thinking skills. Recent evidence
suggests that in those people who have thinking difficulties, effective treatment and
improvement of depression can also result in improved thinking skills. Therefore, a test of
thinking skills is included in this study.
This study will also evaluate three other potential indicators of treatment response:
cortisol, cytokines, and grip strength.
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Observational Model: Case-Only, Time Perspective: Prospective
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