The Therapeutic Efficacy of Neurofeedback in Depression — neurofeedback  

Depression Clinical Trial

Official title: The Therapeutic Efficacy of Frontal EEG Asymmetry Neurofeedback in Depression

Status Completed

Clinical Trial Summary

The investigators examined the therapeutic efficacy of neurofeedback in depression subjects. The investigators hypothesize that 5 weeks neurofeedback training will be able to alleviate depressive symptoms.

Clinical Trial Description

Subject

• Fulfilled DSM-IV criteria for depressive disorders.

• Persons who had organic disorders were excluded.

• Who had been treated by psychoactive drugs for at least 2 months prior to the study were excluded.

Design

• Subjects were randomly assigned to two groups (EEG biofeedback /psychotherapy placebo) by block randomization.

• EEG biofeedback training was provided for 5 weeks(10 sessions, twice per week). Each training session was composed of 6 four minute trials followed by 5 thirty second rest periods

• Psychotherapy placebo session was provided for 5 weeks. These sessions consisted of additional assessment, interpretation of the test results and providing information on course and treatment of mood disorder.

• After subjects completed the training, they participated in a month-long (twice per week) self-training session to maintain a similar mental state during neurofeedback training sessions without feedback system's assistance.

• Subjects who had finished the psychotherapy placebo were referred to other therapists as necessary. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Depression
• Depressive Disorder

• NCT number: NCT00729547
• Study type: Interventional
• Source: Korea University
• Status: Completed
• Phase: N/A
• Start date: September 2006
• Completion date: January 2007