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A Neuroimaging and Epigenetic Investigation of Antidepressants in Depression

Depression Clinical Trial

Official title:
A Neuroimaging and Epigenetic Investigation of Antidepressants in Depression

Clinical Trial Summary

The purpose of this study is:

1. to find out the structural or functional effects of selective serotonin reuptake inhibitors (SSRI) in major depressive disorder (MDD);

2. find special abnormalities in depression secondary to other disease, e.g., autoimmune disease like systemic lupus erythematosus (SLE).

3. find the relationship between the efficacy of antidepressant and the change of neuroimaging in MDD

4. to find possible predispose to MDD

5. to explore the DNA methylation status in depression;

Clinical Trial Description

1. to explore the pathology of depression

2. to identify the difference between MDD and depression secondary to other disease ,especially autoimmune disease

3. to explore the effect of gene-environment interaction on the epigenetic regulation of the depression ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00703742
Study type Interventional
Source Kunming Medical University
Contact
Status Completed
Phase N/A
Start date June 2008
Completion date June 2011
View Details
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